Site‐specific linking of biomolecules via glycan residues using glycosyltransferases
PK Qasba, E Boeggeman… - Biotechnology …, 2008 - Wiley Online Library
The structural information on glycosyltransferases has revealed that the sugar‐donor
specificity of these enzymes can be broadened to include modified sugars with a chemical …
specificity of these enzymes can be broadened to include modified sugars with a chemical …
Control of O-glycan synthesis: specificity and inhibition of O-glycan core 1 UDP-galactose:N-acetylgalactosamine-α-R β3-galactosyltransferase from rat liver
I Brockhausen, G Möller… - … and Cell Biology, 1992 - cdnsciencepub.com
The specificity of glycosyltransferases is a major control factor in the biosynthesis of O-
glycans. The enzyme that synthesizes O-glycan core 1, ie, UDP-galactose: N …
glycans. The enzyme that synthesizes O-glycan core 1, ie, UDP-galactose: N …
Enzymic transfer of 6-modified d-galactosyl residues: synthesis of biantennary penta-and hepta-saccharides having two 6-deoxy-d-galactose residues at the …
Y Kajihara, T Endo, H Ogasawara, H Kodama… - Carbohydrate …, 1995 - Elsevier
UDP-6-Deoxy-d-galactose and UDP-6-deoxy-6-fluoro-d-galactose were synthesized and
their transfer to 2-acetamido-2-deoxy-d-glucose (N-acetyl-d-glucosamine) by β-(1→ 4) …
their transfer to 2-acetamido-2-deoxy-d-glucose (N-acetyl-d-glucosamine) by β-(1→ 4) …
Chemical rescue of α3-galactosyltransferase. Implications in the mechanism of retaining glycosyltransferases
A Monegal, A Planas - Journal of the American Chemical Society, 2006 - ACS Publications
The mechanism of retaining glycosyltransferases is still poorly understood and the subject of
current debate. Both double displacement and front side single displacement (SNi) …
current debate. Both double displacement and front side single displacement (SNi) …
Transfer of galactose to the anomeric position of N-acetyl gentosamine by galactosyltransferase from bovine milk
Y Nishida, T Wiemann, J Thiem - Tetrahedron letters, 1992 - Elsevier
Transfer of Galactose to the Anomeric Position of N-Acetyl Gentosamine by
Galactosyltransferase from Bovine Milk 8043 Page 1 Tcuahc&onLcttcm.Vol. 33.No.52,pp.8043-8046.1992 …
Galactosyltransferase from Bovine Milk 8043 Page 1 Tcuahc&onLcttcm.Vol. 33.No.52,pp.8043-8046.1992 …
β-1, 4-Galactosyltransferase-catalyzed glycosylation of sugar derivatives: Modulation of the enzyme activity by α-lactalbumin, immobilization and solvent tolerance
A Pišvejcová, C Rossi, L Hušáková, V Křen… - Journal of Molecular …, 2006 - Elsevier
The influence of different parameters on the activity of the β-1, 4-galactosyltransferase (β-1,
4-GalT) from bovine milk has been investigated using various acceptor and donor …
4-GalT) from bovine milk has been investigated using various acceptor and donor …
Acceptor-substrate recognition by N-acetylglucosaminyltransferase-V: Critical role of the 4 ″-hydroxyl group in β-D-GlcpNAc-(1→ 2)-α-D-Manp (1→ 6)-β-D-Glcp-OR
O Kanie, SC Crawley, MM Palcic, O Hindsgaul - Carbohydrate research, 1993 - Elsevier
The enzyme N-acetylglucosaminyltransferase-V (GlcNAcT-V) transfers GlcNAc from UDP-
GlcNAc to the OH-6′ group of oligosaccharides terminating in the sequence β-d-GlcpNAc …
GlcNAc to the OH-6′ group of oligosaccharides terminating in the sequence β-d-GlcpNAc …
Thermodynamic insights into the structural basis governing the donor substrate recognition by human β1, 4-galactosyltransferase 7
F Daligault, S Rahuel-Clermont, S Gulberti… - Biochemical …, 2009 - portlandpress.com
Human β1, 4-GalT (galactosyltransferase) 7 is involved in the biosynthesis of the
tetrasaccharide linker protein region (GlcAβ1→ 3Galβ1→ 3Galβ1→ 4Xylβ1)(where GlcA is …
tetrasaccharide linker protein region (GlcAβ1→ 3Galβ1→ 3Galβ1→ 4Xylβ1)(where GlcA is …
Synthesis of novel disaccharides based on glycosyltransferases: β1, 4galactosyltransferase
CH Wong, T Krach, C Gautheron-Le Narvor… - Tetrahedron letters, 1991 - Elsevier
Abstract β1, 4Galactosyltransferase and β-galactosidase have been investigated with regard
to their acceptor specificity and used in the synthesis of galactosides using 5-thioglucose …
to their acceptor specificity and used in the synthesis of galactosides using 5-thioglucose …
Improving solubility of catalytic domain of human β‐1, 4‐galactosyltransferase 1 through rationally designed amino acid replacements
M Malissard, EG Berger - European journal of biochemistry, 2001 - Wiley Online Library
β‐1, 4‐galactosyltransferase 1 (β4gal‐T1, EC 2.4. 1.38) transfers galactose from UDP‐
galactose to free N‐acetyl‐d‐glucosamine or bound N‐acetyl‐d‐glucosamine‐R. Soluble …
galactose to free N‐acetyl‐d‐glucosamine or bound N‐acetyl‐d‐glucosamine‐R. Soluble …