Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2023 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between two disease entities has received extensive acknowledgment, yet …

Depression in Alzheimer's disease: epidemiology, mechanisms, and management

S Chi, JT Yu, MS Tan, L Tan - Journal of Alzheimer's disease, 2014 - content.iospress.com
Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …

What is the association between depression and Alzheimer's disease?

N Tsuno, A Homma - Expert review of neurotherapeutics, 2009 - Taylor & Francis
Depression and dementia, in particular Alzheimer's disease (AD), are critically important
issues in the mental health of old age. Both conditions apparently reduce quality of life and …

Depression—an underrecognized target for prevention of dementia in Alzheimer's disease

FS Dafsari, F Jessen - Translational psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …

Depression in Alzheimer's disease: heterogeneity and related issues

HB Lee, CG Lyketsos - Biological psychiatry, 2003 - Elsevier
Several studies have demonstrated that the great majority of Alzheimer's disease (AD)
patients suffer “noncognitive” neuropsychiatric symptoms. Depression is one of the most …

Depression in Alzheimer's disease: overview and treatment

CG Lyketsos, J Olin - Biological psychiatry, 2002 - Elsevier
Psychiatric disturbances affect as many as 90% of patients with Alzheimer's disease (AD)
and are a major focus of treatment. Depression is one of the most frequent psychiatric …

Depression and risk of developing dementia

AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …

Distinguishing features of depression in dementia from primary psychiatric disease

DW Fisher, JT Dunn, H Dong - Discover Mental Health, 2024 - Springer
Depression is a common and devastating neuropsychiatric symptom in the elderly and in
patients with dementia. In particular, nearly 80% of patients with Alzheimer's Disease …

Depression as a risk factor for Alzheimer's disease: Genes, steroids, cytokines and neurogenesis–What do we need to know?

J Herbert, PJ Lucassen - Frontiers in neuroendocrinology, 2016 - Elsevier
Depression (MDD) is prodromal to, and a component of, Alzheimer's disease (AD): it may
also be a trigger for incipient AD. MDD is not a unitary disorder, so there may be particular …

Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis

RL Ownby, E Crocco, A Acevedo, V John… - Archives of general …, 2006 - jamanetwork.com
Context A history of depression may increase risk for developing Alzheimer disease (AD)
later in life. Clarifying this relation might improve understanding of risk factors for and …