Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones
Obesity increases the risk of many cancers in both males and females. This study describes
a link between obesity, obesity-associated metabolic alterations, and the risk of developing …
a link between obesity, obesity-associated metabolic alterations, and the risk of developing …
Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones
NP Núñez, SN Perkins, NCP Smith, D Berrigan… - Nutrition and …, 2008 - Taylor & Francis
Obesity increases incidence and mortality of breast cancer in postmenopausal women.
Mechanisms underlying this association are poorly understood. Suitable animal models are …
Mechanisms underlying this association are poorly understood. Suitable animal models are …
Differential susceptibility to obesity between male, female and ovariectomized female mice
J Hong, RE Stubbins, RR Smith, AE Harvey, NP Núñez - Nutrition journal, 2009 - Springer
Background The prevalence of obesity has increased dramatically. A direct comparison in
the predisposition to obesity between males, premenopausal females, and postmenopausal …
the predisposition to obesity between males, premenopausal females, and postmenopausal …
Effects of obesity on hormonally driven cancer in women
KH Moley, GA Colditz - Science translational medicine, 2016 - science.org
Obesity increases the risk of numerous poor health outcomes, including cancer. Obesity is
especially problematic in women because both they and their offspring may be at increased …
especially problematic in women because both they and their offspring may be at increased …
Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer
Obese postmenopausal women have increased risk of breast cancers with poorer clinical
outcomes than their lean counterparts. However, the mechanisms underlying these …
outcomes than their lean counterparts. However, the mechanisms underlying these …
Energy balance modulates colon tumor growth: interactive roles of insulin and estrogen
EA Rondini, AE Harvey, JP Steibel… - Molecular …, 2011 - Wiley Online Library
Obesity increases colorectal cancer (CRC) risk and progression. However, the impact of
obesity on CRC in women is dependent on ovarian hormone status. The purpose of this …
obesity on CRC in women is dependent on ovarian hormone status. The purpose of this …
Diet-induced obesity and mammary tumor development in MMTV-neu female mice
MP Cleary, JP Grande, SC Juneja… - Nutrition and cancer, 2004 - Taylor & Francis
Obesity is a risk factor for postmenopausal breast cancer and is associated with shortened
latency and/or increased mammary tumor (MT) incidence in animals. Elevated body weight …
latency and/or increased mammary tumor (MT) incidence in animals. Elevated body weight …
Obesity and cancer
H Ungefroren, F Gieseler, S Fliedner… - … molecular biology and …, 2015 - degruyter.com
The incidence of obesity in the Western world has increased dramatically during the recent
decades. Epidemiological data suggest that obesity is associated with an increased risk of …
decades. Epidemiological data suggest that obesity is associated with an increased risk of …
The obesity-cancer link: lessons learned from a fatless mouse
SD Hursting, NP Nunez, L Varticovski, C Vinson - Cancer research, 2007 - AACR
Current dogma suggests that the positive correlation between obesity and cancer is driven
by white adipose tissue that accompanies obesity, possibly through excess secretion of …
by white adipose tissue that accompanies obesity, possibly through excess secretion of …
Obesity increases tumor aggressiveness in a genetically engineered mouse model of serous ovarian cancer
Objectives Obesity is associated with increased risk and worse outcomes for ovarian cancer.
Thus, we examined the effects of obesity on ovarian cancer progression in a genetically …
Thus, we examined the effects of obesity on ovarian cancer progression in a genetically …
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