Contact inhibition of locomotion (CIL), the repulsive response of cells upon cell–cell contact,
has been the predominant paradigm for contact-mediated responses. However, it is difficult …

the substratum, we proposed that the actin cables could not become assembled in a bent
state and hence the cfficiency with which the cell could exert traction on the substratum was …

Immune cells have the ubiquitous capability to migrate disregarding the adhesion properties
of the environment, which requires a versatile adaptation of their adhesiveness mediated by …

In recent years, research utilizing micro-and nanoscale geometries and structures on
biomaterials to manipulate cellular behaviors, such as differentiation, proliferation, survival …

Collective migration of cells is of fundamental importance for a number of biological
functions such as tissue development and regeneration, wound healing and cancer …

The spatial organization of cell–cell adherens junctions is distinct in cultured cells from two
different tissue types, specifically, epitheliocytes and fibroblasts. In epitheliocytes, contacts …

Growth cones interact with the extracellular matrix (ECM) through integrin receptors at
adhesion sites termed point contacts. Point contact adhesions link ECM proteins to the actin …

How adherent and contractile systems coordinate to promote cell shape changes is unclear.
Here, we define a counterbalanced adhesion/contraction model for cell shape control. Live …

By placing stiff structures under soft materials, prior studies have demonstrated that cells
sense and prefer to position themselves over the stiff structures. However, an understanding …

Micrometer and nanometer grooved surfaces have been determined to influence cellular
orientation, morphology, and migration through contact guidance. Cells typically elongate …