Collective cell movement is critical in pathological processes such as wound healing and
cancer invasion. It entails complex interactions between adjacent cells and between cells …

Whether to spread on a surface or to crawl, cells must apply traction forces to the underlying
substrate via adhesion complexes. In this issue, Pontes et al.(2017. J. Cell Biol. https://doi …

The behavior and fate of tissue cells are controlled by the rigidity and geometry of their
adhesive environment, possibly through forces localized to sites of adhesion. We introduce …

Migration of a fibroblast along a collagen fiber can be regarded as cell locomotion in one-
dimension (1D). In this process, a cell protrudes forward, forms a new adhesion, produces …

Fibroblast migration involves complex mechanical interactions with the underlying substrate.
Although tight substrate contact at focal adhesions has been studied for decades, the role of …

Cancer cell migration is essential for metastasis, during which cancer cells move through the
tumor and reach the blood vessels. In vivo, cancer cells are exposed to contact guidance …

The topography of material surface has important influence on cell behavior and
physiological functions. Groove-like pattern has drawn much attention among various …

Cell adhesion to the extracellular matrix (ECM) is highly active and plays a crucial role in
various physiological functions. The active response of cells to physicochemical cues has …

Metazoan development relies on the formation and remodeling of cell-cell contacts.
Dynamic reorganization of adhesion receptors and the actomyosin cell cortex in space and …

In this report, we describe using ultraviolet (UV)-assisted capillary force lithography (CFL) to
create a model substratum of anisotropic micro-and nanotopographic pattern arrays with …