High WDR34 mRNA expression as a potential prognostic biomarker in patients with breast cancer as determined by integrated bioinformatics analysis

DJ Hu, WJ Shi, M Yu, L Zhang - Oncology Letters, 2019 - spandidos-publications.com
The WD‑repeat domain (WDR) family is distributed in the majority of eukaryotes and has
several unique biological functions. It serves important roles in signal transduction …

Systematic analysis of the oncogenic role of WDR62 in human tumors

Y Bu, L Zhang, X Ma, R Wang, X Zhang, J Li - Disease Markers, 2021 - Wiley Online Library
Background. Emerging studies support the oncogenic role of WD repeat domain 62
(WDR62) in few tumors, while no pan‐cancer analysis is available. In this study, we …

Aberrant methylation of WD‐repeat protein 41 contributes to tumour progression in triple‐negative breast cancer

H Wang, D Wu, L Cai, X Li, Z Zhang… - Journal of Cellular and …, 2020 - Wiley Online Library
WD‐repeat proteins are implicated in a variety of biological functions, most recently in
oncogenesis. However, the underlying function of WD‐repeat protein 41 (WDR41) in …

Integrative analysis of WDR12 as a potential prognostic and immunological biomarker in multiple human tumors

RA Eid, MA Eldeen, MA Soltan, M Al-Shraim… - Frontiers in …, 2023 - frontiersin.org
Background: Mammalian WD-repeat protein 12 (WDR12), a family member of proteins
containing repeats of tryptophan-aspartic acid (WD), is a potential homolog of yeast Ytm1p …

[HTML][HTML] Effect of high WDR5 expression on the hepatocellular carcinoma prognosis

Z Cui, H Li, F Liang, C Mu, Y Mu… - Oncology …, 2018 - spandidos-publications.com
Abstract WD repeat domain 5 (WDR5) serves an important role in various biological
functions through the epigenetic regulation of gene transcription. Aberrant expression of …

Identification of WD‐Repeat Protein 72 as a Novel Prognostic Biomarker in Non‐Small‐Cell Lung Cancer

G Shi, Q Ni, Y Miao, H Huang, Z Yin… - Mediators of …, 2023 - Wiley Online Library
WD‐repeat protein 72 (WDR72; OMIM∗ 613214), a scaffolding protein lacking intrinsic
enzymatic activity, produces numerous β‐propeller blade formations, serves as a binding …

Identification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation

Y Yin, L Zhou, R Zhan, Q Zhang, M Li - Cancer Management and …, 2018 - Taylor & Francis
Background Hepatocellular carcinoma (HCC) is one of the most common malignant cancer
worldwide. Importantly, the precise mechanisms causing HCC pathogenicity are still …

Up‐regulated WDR5 promotes gastric cancer formation by induced cyclin D1 expression

W Sun, F Guo, M Liu - Journal of cellular biochemistry, 2018 - Wiley Online Library
Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer‐
related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its …

[HTML][HTML] WD40 repeat-containing 62 overexpression as a novel indicator of poor prognosis for human gastric cancer

S Zeng, Y Tao, J Huang, S Zhang, L Shen… - European Journal of …, 2013 - Elsevier
Abstract Aim WD40 repeat-containing 62 (WDR62) is a centrosome-associated gene
involved in cell cycling and proliferation. However, the role of WDR62 in human …

WD repeat domain 43 promotes malignant progression of non-small cell lung cancer by regulating CDK2

H Sun, Q Sun, X Qiu, G Zhang, G Chen, A Li… - The International Journal …, 2022 - Elsevier
Non-small cell lung cancer (NSCLC) ranks highly among malignant tumors in the world in
terms of morbidity and mortality. By using bioinformatics, we screened and obtained a novel …