Molecular links between COPD and lung cancer: new targets for drug discovery?

G Caramori, P Ruggeri, S Mumby, A Ieni… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: COPD and lung cancer are leading causes of morbidity and mortality
worldwide, and they share a common environmental risk factor in cigarette smoke exposure …

Exposing a deadly alliance: novel insights into the biological links between COPD and lung cancer

K Vermaelen, G Brusselle - Pulmonary pharmacology & therapeutics, 2013 - Elsevier
Chronic obstructive pulmonary disease (COPD) affects more than 200 million people
worldwide and is expected to become the third leading cause of death in 2020. COPD is …

Common pathogenic mechanisms and pathways in the development of COPD and lung cancer

IA Yang, V Relan, CM Wright… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Lung cancer and COPD commonly coexist in smokers, and the presence of
COPD increases the risk of developing lung cancer. In addition to smoking cessation and …

Current concepts on the role of inflammation in COPD and lung cancer

H Yao, I Rahman - Current opinion in pharmacology, 2009 - Elsevier
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading cause of death,
and both are associated with cigarette smoke exposure. It has been shown that 50–70% of …

Chronic obstructive pulmonary disease and lung cancer: new molecular insights

IM Adcock, G Caramori, PJ Barnes - Respiration, 2011 - karger.com
Both chronic obstructive pulmonary disease (COPD) and lung cancer are major causes of
death worldwide. In most cases this reflects cigarette smoke exposure which is able to …

[HTML][HTML] New biomarkers and therapeutics can be discovered during COPD-lung cancer transition

X Wang - Cell biology and toxicology, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) has been found to be associated with lung
cancer regardless of a patient's smoking history. Of 11,888 incident cases of lung cancer …

[HTML][HTML] Biological and genetic mechanisms of COPD, its diagnosis, treatment, and relationship with lung cancer

KH Czarnecka-Chrebelska, D Mukherjee… - Biomedicines, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent chronic adult
diseases, with significant worldwide morbidity and mortality. Although long-term tobacco …

Chronic obstructive pulmonary disease and lung cancer: underlying pathophysiology and new therapeutic modalities

MS Eapen, PM Hansbro, AK Larsson‑Callerfelt… - Drugs, 2018 - Springer
Chronic obstructive pulmonary disease (COPD) and lung cancer are major lung diseases
affecting millions worldwide. Both diseases have links to cigarette smoking and exert a …

[HTML][HTML] Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis

BA Parris, HE O'Farrell, KM Fong… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) and lung cancer comprise the leading
causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual …

[HTML][HTML] The relationship between COPD and lung cancer

AL Durham, IM Adcock - Lung cancer, 2015 - Elsevier
Both COPD and lung cancer are major worldwide health concerns owing to cigarette
smoking, and represent a huge, worldwide, preventable disease burden. Whilst the majority …