Causes of clonal hematopoiesis: a review
Abstract Purpose of Review Clonal hematopoiesis (CH) is an age-dependent process
detectable using advanced sequencing technologies and is associated with multiple …
detectable using advanced sequencing technologies and is associated with multiple …
[PDF][PDF] Regulators of clonal hematopoiesis and physiological consequences of this condition
Clonal hematopoiesis (CH) is a prevalent condition that results from somatic mutations in
hematopoietic stem cells. When these mutations occur in “driver” genes, they can potentially …
hematopoietic stem cells. When these mutations occur in “driver” genes, they can potentially …
Clinical and Therapeutic Implications of Clonal Hematopoiesis
G Petrone, I Turker, P Natarajan… - Annual Review of …, 2024 - annualreviews.org
Clonal hematopoiesis (CH) is an age-related process whereby hematopoietic stem and
progenitor cells (HSPCs) acquire mutations that lead to a proliferative advantage and clonal …
progenitor cells (HSPCs) acquire mutations that lead to a proliferative advantage and clonal …
The clinical management of clonal hematopoiesis: creation of a clonal hematopoiesis clinic
Hematol Oncol Clin N Am 34 (2020) 357–367 https://doi. org/10.1016/j. hoc. 2019.11. 006
hemonc. theclinics. com 0889-8588/20/© 2019 Elsevier Inc. All rights reserved. phenotype …
hemonc. theclinics. com 0889-8588/20/© 2019 Elsevier Inc. All rights reserved. phenotype …
Clonal hematopoiesis: a shared risk factor for cardiovascular diseases and tumors
LF Zha, X Cheng - Oncology and Translational Medicine, 2024 - journals.lww.com
Clonal hematopoiesis (CH) is a clonally expanded population of hematopoietic stem cells
carrying somatic mutations that differentiate through multilineage hematopoiesis to form …
carrying somatic mutations that differentiate through multilineage hematopoiesis to form …
Germline Predisposition for Clonal Hematopoiesis
Clonal hematopoiesis (CH) is an entity hallmarked by skewed hematopoiesis with persistent
overrepresentation of cells from a common stem/progenitor lineage harboring single …
overrepresentation of cells from a common stem/progenitor lineage harboring single …
[HTML][HTML] Decoding Clonal Hematopoiesis: Emerging Themes and Novel Mechanistic Insights
S Pendse, D Loeffler - Cancers, 2024 - mdpi.com
Simple Summary The expansion of mutant cells that outgrow and displace normal blood
cells is called clonal hematopoiesis (CH). CH starts with the acquisition of mutations in blood …
cells is called clonal hematopoiesis (CH). CH starts with the acquisition of mutations in blood …
Germline risk of clonal haematopoiesis
Clonal haematopoiesis (CH) is a common, age-related expansion of blood cells with
somatic mutations that is associated with an increased risk of haematological malignancies …
somatic mutations that is associated with an increased risk of haematological malignancies …
Clonal hematopoiesis in survivors of childhood cancer
D Novetsky Friedman, ICC Chan… - Blood …, 2023 - ashpublications.org
Clonal hematopoiesis (CH), defined as the clonal expansion of mutated hematopoietic stem
and progenitor cells, is associated with the development of hematologic cancers …
and progenitor cells, is associated with the development of hematologic cancers …
Novel associations between clonal hematopoiesis and therapeutic exposures revealed in patients with solid tumors using real world evidence
A Sonnenschein, E Moore, C Lo, P Kang, TJ Taxter… - Blood, 2022 - ashpublications.org
Clonal hematopoiesis (CH) occurs when somatic mutations confer a fitness advantage in
blood cells enabling them to outcompete, increases with age, and has been linked to greater …
blood cells enabling them to outcompete, increases with age, and has been linked to greater …
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