The cardiovascular effects of estrogen are mediated in part by augmenting the function of
endothelial nitric oxide synthase. Endothelial nitric oxide synthase activity is dependent on …

This paper reviews the evidence for calcium-antagonist properties of oestrogen which may
offer long-term protective effects on the cardiovascular system in postmenopausal women …

Background We wished to investigate the possible mechanism of the protective effect of
estrogen replacement on coronary atherosclerosis observed in postmenopausal women …

One mechanism by which the female sex may protect against elevated coronary vascular
tone is inhibition of Ca2+ entry into arterial smooth muscle cells (ASMC s). In vitro findings …

Ethinyl estradiol (EE2), administered orally to ovariectomized (ovex) rats, has been shown to
prevent loss of bone mineral density and to decrease serum cholesterol levels. Radioligand …

Pregnancy is associated with decreased vascular responsiveness to vasopressor stimuli.
We have tested the involvement of Ca2+ mobilization in myotropic responses of aortic rings …

Catecholamine-induced vascular smooth muscle contration is enhanced in female animals
and in presence of emale sex hormones in vitro. Androgens appear to depress these …

Abstract 17β-Estradiol (E 2) plays an important role in Ca 2+ fluxes in several cell types. It
has been proposed that some of its effects are of nongenomic origin E 2 at vascular smooth …

The protective effects of 17p oestradiol against the onset of atherosclerosis in women can
only partly be explained by altered lipid metabolism. The vessel wall itself is also a target …

Gender-based differences in cardiovascular mortality may be due to a cardio-protective
effect of oestrogens on the myocardium. However, mRNA expression of oestrogen receptors …