Even after optimal treatment with and response to antidepressant medications during acute
treatment of major depressive disorder, residual symptoms are common. Patients with …

Full remission should be the goal of antidepressant therapy; anything less leaves the patient
with residual symptoms and an increased risk of relapse and recurrence. Most …

Depression is the fourth-largest contributor to the global burden of disease, and it causes
profound suffering and extreme costs to health care systems and society. Although there …

E ity, and perceived effectiveness of these medications have dramatically increased public
awareness of depression as a serious illness and have contributed to the increase in …

A paradigm shift in the management of depression has transpired in recent years with the
modification of treatment goals toward remission, an outcome that transcends response …

Historically, the emphasis in treating depression has been focused on the acute phase of
treatment, with few published data on the continuation and maintenance phases of …

A meta-analysis of an earlier multicenter, double-blind efficacy study comparing placebo,
oxaprotiline and amitriptyline was performed in order to test the survival-analytical approach …

The onset of action of antidepressant drugs was investigated on the basis of two
independent multicenter, double-blind efficacy studies comparing amitriptyline (n= 120) …

The onset of action of antidepressant drugs was investigated on the basis of two
independent, multicenter, double-blind studies, comparing amitriptyline (N= 120) …

Three types of early termination Of antidepressant Page 1 International Cliniai shphrol 093),
83536 Three types of early termination Of antidepressant drug treatment M Linden M …