Clonal proliferation within smooth muscle cells in unstable human atherosclerotic lesions
K Kawai, A Sakamoto, M Mokry… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Studies in humans and mice using the expression of an X-linked gene or
lineage tracing, respectively, have suggested that clones of smooth muscle cells (SMCs) …
lineage tracing, respectively, have suggested that clones of smooth muscle cells (SMCs) …
Reconciling smooth muscle cell oligoclonality and proliferative capacity in experimental atherosclerosis
D Gomez, GK Owens - Circulation research, 2016 - Am Heart Assoc
Gomez and Owens SMC Clonal Expansion in Atherosclerosis 1263 wild-type cells might
undergo selective clonal expansion or selection and end up being the dominant cell type …
undergo selective clonal expansion or selection and end up being the dominant cell type …
Phenotypic heterogeneity of smooth muscle cells–implications for atherosclerosis
M Coen, ML Bochaton‐Piallat - Atherosclerosis: Molecular and …, 2010 - Wiley Online Library
During atherosclerosis, local secretion of chemokines and growth factors following
endothelial injury, adhesion of platelets, and infiltration of inflammatory cells into the intima …
endothelial injury, adhesion of platelets, and infiltration of inflammatory cells into the intima …
[HTML][HTML] Role of vascular smooth muscle cell clonality in atherosclerosis
Atherosclerotic cardiovascular disease remains the leading cause of death worldwide. While
many cell types contribute to the growing atherosclerotic plaque, the vascular smooth …
many cell types contribute to the growing atherosclerotic plaque, the vascular smooth …
Evidence for cultured human vascular smooth muscle cell heterogeneity: isolation of clonal cells and study of their growth characteristics
The monoclonal theory of atherosclerosis postulates that the initial vascular smooth muscle
cell (VSMC) proliferative event involves the expansion of a single cell or a sub-population of …
cell (VSMC) proliferative event involves the expansion of a single cell or a sub-population of …
Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development
H Hao, G Gabbiani… - … , thrombosis, and vascular …, 2003 - Am Heart Assoc
During atheromatous plaque formation or restenosis after angioplasty, smooth muscle cells
(SMCs) migrate from the media toward the intima, where they proliferate and undergo …
(SMCs) migrate from the media toward the intima, where they proliferate and undergo …
Smooth muscle cell phenotypes in atherosclerotic lesions
CM Shanahan, PL Weissberg - Current opinion in lipidology, 1999 - journals.lww.com
Recently, there has been a dramatic change in the way we think about the role of vascular
smooth muscle cells in atherosclerosis, and it is now generally accepted that a dearth of …
smooth muscle cells in atherosclerosis, and it is now generally accepted that a dearth of …
[HTML][HTML] Smooth muscle cell outgrowth from human atherosclerotic plaque: implications for the assessment of lesion biology
JG Pickering, L Weir, K Rosenfield, J Stetz… - Journal of the American …, 1992 - Elsevier
Objectives. The purpose of this study was to determine whether the kinetics of smooth
muscle cell outgrowth from in vitro explants of human atherosclerotic tissue is dependent on …
muscle cell outgrowth from in vitro explants of human atherosclerotic tissue is dependent on …
A method to isolate morphologically distinct clones of smooth muscle cells from human saphenous vein
Z Wang, PJ Rao, MR Castresana, WH Newman - Methods in cell science, 2002 - Springer
The monoclonal theory of atherosclerosis postulates that a certain subpopulation of vascular
smooth muscle cells (VSMC) is selectively expanded in response to pathological stimuli …
smooth muscle cells (VSMC) is selectively expanded in response to pathological stimuli …
Vascular smooth muscle cells in atherosclerosis
MR Bennett, S Sinha, GK Owens - Circulation research, 2016 - Am Heart Assoc
The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that
aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced …
aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced …