Objective: To examine the relationship between sperm chromatin defects, evaluated by the
flow cytometric (FCM) sperm chromatin structure assay (SCSA), and the probability of a …

The impact of demographic, lifestyle, and seminal factors on the sperm chromatin structure
assay (SCSA) parameters was evaluated in a population of 277 healthy Danish men. This …

The SCSA® is the pioneering assay for the detection of damaged sperm DNA and altered
proteins in sperm nuclei via flow cytometry of acridine orange (AO) stained sperm. The …

The integrity of the paternal genome is essential as the spermatozoon can bring genetic
damage into the oocyte at fertilization and contribute to the development of abnormal …

In this context, sperm chromatin abnormalities have been studied extensively in past
decades as a cause of male infertility. The authors provide the rationale for sperm chromatin …

OBJECTIVE: To evaluate the association between chromatin structure and sperm motility.
DESIGN: Cross-sectional prospective study. SETTING: Scanian Andrology Centre, Malmö …

The sperm chromatin structure assay (SCSA) was used to measure over 500 human semen
samples from two independent studies: Study I, 402 samples from 165 presumably fertile …

OBJECTIVE: To investigate the relationship between sperm chromatin structure assay
(SCSA) parameters, DNA fragmentation index (DFI) and high DNA stainability (HDS), and …

Abstract The Sperm Chromatin Structure Assay (SCSA®) is a federally registered protocol
for simultaneous flow cytometric measures of sperm DNA integrity and chromatin structure …

Aim: Sperm chromatin/DNA integrity is essential for the accurate transmission of paternal
genetic information, and normal sperm chromatin structure is important for sperm fertilizing …