The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

A panoramic view of RNA modifications: exploring new frontiers | Genome Biology Skip to
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Proper control of the transcriptome is key for diverse aspects of gene expression, cellular
functions and development, and its disruption can result in disease. A rapidly accumulating …

The discovery of mechanisms that alter genetic information via RNA editing or introducing
covalent RNA modifications points towards a complexity in gene expression that challenges …

In the past few years, thorough investigation of chemical modifications operated in the cells
on ribonucleic acid (RNA) molecules is gaining momentum. This new field of research has …

In the last decade, the notion that mRNA modifications are involved in regulation of gene
expression was demonstrated in thousands of studies. To date, new technologies and …

The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C, A, G, and U in
RNA. Triplets of these four letters jointly encode 20 different amino acids out of which …

Gene regulation depends on dynamic and reversibly modifiable biological and chemical
information in the epigenome/epitranscriptome. Accumulating evidence suggests that …

Post-transcriptional RNA modification occurs on all types of RNA and plays a vital role in
regulating every aspect of RNA function. Thanks to the development of high-throughput …

With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …