In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy

IO Evbuomwan, OO Alejolowo, TC Elebiyo… - Journal of …, 2024 - Taylor & Francis
The emergence of varying levels of resistance to currently available antimalarial drugs
significantly threatens global health. This factor heightens the urgency to explore bioactive …

Isolation and structure elucidation of a steroidal moiety from Withania somnifera and in silico evaluation of antimalarial efficacy against artemisinin resistance …

D Pradhan, P Biswasroy, DK Sahu… - Journal of …, 2023 - Taylor & Francis
According to the 2021 Malaria report, 241 million clinical episodes with 627000 deaths
penalty was estimated across the worldwide. However, mutation in the propeller domain of …

Molecular modelling approaches can reveal the Molecular interactions established between antimalarial targets of hemozoin pathway and the organic phytochemicals …

S Chaurasia, A Pandey - Natural Product Research, 2024 - Taylor & Francis
Ayurveda, the traditional Indian medical system, has potential applications in early malaria
treatment. In an in silico docking study, 50 phytochemicals from two plants Artocarpus …

[PDF][PDF] In silico Evaluation of the Inhibitory Potential of Cymbopogonol from Cymbopogon citratus Towards Falcipain-2 (FP2) Cysteine Protease of Plasmodium …

ET Adetobi, SO Akinsuyi, OA Ahmed… - Tropical Journal of …, 2022 - researchgate.net
Antimicrobial resistance is a major challenge militating against the health of people globally.
Plasmodium falciparum has developed resistance to current drugs used in tackling malaria …

Bisbenzylisoquinolines from Cissampelos pareira L. as antimalarial agents: Molecular docking, pharmacokinetics analysis, and molecular dynamic simulation studies

PS Suresh, V Kesarwani, S Kumari, R Shankar… - … Biology and Chemistry, 2023 - Elsevier
Malaria is a major global health issue due to the emergence of resistance to most of the
available antimalarial drugs. There is an urgent need to discover new antimalarials to tackle …

In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite

CA Lobato-Tapia, Y Moreno-Hernández… - Molecules, 2023 - mdpi.com
Malaria is a disease that affects many people in the world. In Mexico, malaria remains an
active disease in certain regions, particularly in the states of Chiapas and Chihuahua. While …

Natural products for treatment of Plasmodium falciparum malaria: An integrated computational approach

ZT Muhseen, AR Hameed, O Al-Bhadly… - Computers in Biology …, 2021 - Elsevier
Malaria is a life-threatening infectious disease with an estimated 229 million cases in the
year 2019 worldwide. Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate …

In Silico Approach Triterpene Glycoside of H. atra Targeting Orotidine 5‐Monophosphate Decarboxylase Protein (PfOMPDC) in P. falciparum Infection Mechanism

PD Utami, H Setianingsih… - BioMed Research …, 2024 - Wiley Online Library
This study accessed the potential antimalarial activity of triterpene glycoside of H. atra
through targeting orotidine 5‐monophosphate decarboxylase protein (PfOMPDC) in P …

In silico studies of bioactive compounds selected from four african plants with inhibitory activity against plasmodium falciparum dihydrofolate reductase-thymidylate …

I Akinwumi, A Faleti, A Owojuyigbe, F Raji… - Journal of Advanced …, 2022 - journals.ekb.eg
Objective: This present study aims to assess in silico inhibitory potentials of bioactive
compounds present in Vernonia amygdalina (Bitter leaf), Cymbopogon citratus …

Antimalarial potential, LC–MS secondary metabolite profiling and computational studies of Zingiber officinale

KO Faloye, MK Tripathi, SA Adesida… - Journal of …, 2024 - Taylor & Francis
Malaria is among the top-ranked parasitic diseases that pose a threat to the existence of the
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …