Major depression is a worldwide psychiatric disorder associated with high levels of disability
and various comorbidities. Despite the wide range of antidepressants available, they all …

Purpose: Many patients look to complementary and alternative medicine for a herbal
solution to depression. This literature review summarizes recently published research on the …

A number of clinical studies conducted over the past few years have indicated that whole
extract of St John's wort (Hypericum perforatum L.) has antidepressant effects. The herbal …

Herbal medicine is increasingly used in depressed patients. The purpose of this
retrospective controlled study was to evaluate the efficacy and safety of herbal medicine …

Depressive disorders are very common in clinical practice, with approximately 11.3 of all
adults afflicted during any a year. Saffron is the world's most expensive spice and apart from …

Background Major depressive disorder (MDD) is the most common disorder in our
community. Hypericum perforatumm, is a herb with a long application history in treating …

We present a systematic review of observational studies of hypericum extracts in the
treatment of depressive disorders. We included non-randomized studies with at least 100 …

Introduction: Saffron (Crocus sativus L.) has demonstrated antidepressant effects in clinical
studies and extensive anxiolytic effects in experimental animal models. Methods: 66 patients …

Objective The medicinal plants Rhodiola rosea L.(rhodiola, golden root) and Crocus sativus
L.(saffron) have been shown separately to induce significant effects in depression. The …

Depression, anxiety, stress, and other mental disorders, which are on the rise worldwide, are
indications that pharmacological therapy can have serious adverse effects, which is why …