Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Chronic rhinosinusitis (CRS) is a complex disease consisting of several disease variants
with different underlying pathophysiologies. Limited knowledge of the mechanisms of these …

Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of
the paranasal sinuses and upper airway that has substantial associated health care costs …

Objective With the advent of new treatment options for Chronic Rhinosinusitis (CRS) comes
the ability for physicians to provide more individualized patient care. Physicians are now …

It is increasingly recognized that chronic rhinosinusitis (CRS) comprises a spectrum of
different diseases with distinct clinical presentations and pathogenic mechanisms. Defining …

Chronic rhinosinusitis can be differentiated into several phenotypes based on clinical
criteria; however, these phenotypes do not teach us much about the underlying inflammatory …

Background Chronic rhinosinusitis (CRS) is a complex disease that incorporates many
different conditions. Currently, primary CRS is considered a disease of broad airway …

Chronic rhinosinusitis (CRS) is a complex heterogeneous disease with different phenotypes
and endotypes. Recent advances in our understanding of the pathogenetic mechanisms of …

Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease with various
underlying pathophysiologic mechanisms which translate to endotypes, in contrast to clinical …

Abstract Purpose of Review Chronic rhinosinusitis (CRS) is a heterogenous disease
process affecting a significant proportion of the population and impacting quality of life and …