Due to well-conducted epidemiological studies and advances in genetics, molecular
biology, translational research, the advent of computed tomography of the lungs and …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide and a significant challenge for adult physicians. However, there is a …

COPD, characterized by long-term poorly irreversible airway limitation and persistent
respiratory symptoms, has resulted in enormous challenges to human health worldwide …

Chronic obstructive pulmonary disease (COPD) is conventionally thought of as a disease of
adult smokers, related to airway inflammation and structural airway changes (remodeling) …

Chronic obstructive pulmonary disease (COPD) continues to cause a heavy health and
economic burden around the world. Recent studies have added evidence to the etiologic …

The natural history of COPD is complex, and the disease is best understood as a syndrome
resulting from numerous interacting factors throughout the life cycle with smoking being the …

Chronic obstructive pulmonary disease (COPD) has been a major public health problem
during the 20th century, and will remain a challenge for the foreseeable future. Worldwide …

A genetic contribution to develop chronic obstructive pulmonary disease (COPD) is well
established. However, the specific genes responsible for enhanced risk or host differences …

Chronic obstructive pulmonary disease (COPD) is a leading cause of world-wide mortality
and disability. On average∼ 5–15% of adults in industrialized countries have COPD defined …

There is increasing interest in the origins of chronic obstructive pulmonary disease (COPD),
as it is envisaged that preventive efforts and treatment can modify its clinical course. The …