Involvement of cholinergic, adrenergic, and glutamatergic network modulation with cognitive dysfunction in Alzheimer's disease
Alzheimer's disease (AD), the most common cause of dementia, is a progressive
neurodegenerative disease. The number of AD cases has been rapidly growing worldwide …
neurodegenerative disease. The number of AD cases has been rapidly growing worldwide …
NMDA neurotransmission dysfunction in mild cognitive impairment and Alzheimer's disease
The prevalence of Alzheimer's disease (AD) in the elderly is growing rapidly worldwide, and
the deteriorating clinical course of AD places a heavy burden on both the patients and their …
the deteriorating clinical course of AD places a heavy burden on both the patients and their …
The dual role of glutamatergic neurotransmission in Alzheimer's disease: from pathophysiology to pharmacotherapy
Alzheimer's disease (AD) is an age-related dementia and neurodegenerative disorder,
characterized by Aβ and tau protein deposition impairing learning, memory and suppressing …
characterized by Aβ and tau protein deposition impairing learning, memory and suppressing …
Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease
D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …
cause of progressive dementia in senior adults. It is characterized by memory loss and …
Neurotransmitters in prevention and treatment of Alzheimer's disease
Z Yang, Y Zou, L Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of cognitive impairment in middle-aged
and older populations. There is a lack of drugs that demonstrate significant efficacy in AD, so …
and older populations. There is a lack of drugs that demonstrate significant efficacy in AD, so …
Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease
Y Xu, J Yan, P Zhou, J Li, H Gao, Y Xia, Q Wang - Progress in neurobiology, 2012 - Elsevier
Cognitive dysfunction is one of the most typical characteristics in various neurodegenerative
diseases such as Alzheimer's disease and Parkinson's disease (advanced stage). Although …
diseases such as Alzheimer's disease and Parkinson's disease (advanced stage). Although …
Amyloid-β, tau, and the cholinergic system in Alzheimer's disease: Seeking direction in a tangle of clues
A Majdi, S Sadigh-Eteghad… - Reviews in the …, 2020 - degruyter.com
The link between histopathological hallmarks of Alzheimer's disease (AD), ie amyloid
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …
Cognitive decline in neuronal aging and Alzheimer's disease: role of NMDA receptors and associated proteins
J Avila, M Llorens-Martín, N Pallas-Bazarra… - Frontiers in …, 2017 - frontiersin.org
Molecular changes associated with neuronal aging lead to a decrease in cognitive capacity.
Here we discuss these alterations at the level of brain regions, brain cells, and brain …
Here we discuss these alterations at the level of brain regions, brain cells, and brain …
Role of Aβ in Alzheimer's-related synaptic dysfunction
H Zhang, X Jiang, L Ma, W Wei, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Synaptic dysfunction is closely related to Alzheimer's disease (AD) which is also recognized
as synaptic disorder. β-amyloid (Aβ) is one of the main pathogenic factors in AD, which …
as synaptic disorder. β-amyloid (Aβ) is one of the main pathogenic factors in AD, which …
Cross-talk between oxidative stress and modifications of cholinergic and glutaminergic receptors in the pathogenesis of Alzheimer's disease
Z Guan - Acta Pharmacologica Sinica, 2008 - nature.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and its
pathogenesis is likely to be associated with multiple etiologies and mechanisms in which …
pathogenesis is likely to be associated with multiple etiologies and mechanisms in which …
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