The development and progression of chronic obstructive pulmonary disease (COPD) have
been associated with increased oxidative stress or reduced antioxidant resources. Several …

There is a marked increase in oxidative stress in the lungs of patients with COPD, as
measured by increased exhaled 8-isoprostane, ethane, and hydrogen peroxide in the …

An imbalance between oxidants and antioxidants is considered to play a role in the
pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable …

There is now considerable evidence for an increased oxidant burden in patients with chronic
obstructive pulmonary disease (COPD). Oxidative stress is a critical feature in the …

Reactive oxygen species, either directly or via the formation of lipid peroxidation products,
may play a role in enhancing inflammation through the activation of stress kinases (c-Jun …

The respiratory system is continuously exposed to endogenous and exogenous oxidants.
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of …

Chronic obstructive pulmonary disease (COPD) is a progressive condition characterized by
airflow limitation associated with an abnormal inflammatory response of the lungs to noxious …

There is now considerable evidence for an increased oxidant burden in smokers,
particularly in those smokers who develop chronic obstructive pulmonary disease (COPD) …

Smoking is the main etiologic factor in chronic obstructive pulmonary disease (COPD).
Cigarette smoke produces an enormous oxidant burden on the lungs, which is exacerbated …

There is considerable evidence that an increased oxidative burden occurs in the lungs of
patients with chronic obstructive pulmonary disease (COPD) and this results in an …