Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Abstract Background Plasma cell neoplasms (PCNs) encompass a spectrum of disorders
including monoclonal gammopathy of undetermined significance, smoldering myeloma …

We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …

Chromosomal aberrations (CAs) in human peripheral blood lymphocytes (PBL) measured
with the conventional cytogenetic assay have been used for human biomonitoring of …

Numerical and structural chromosomal abnormalities are the hallmarks of cancer. Whereas
the structural chromosome aberrations got more substantial attention for cancer risk …

Background Mosaic loss of Y chromosome (LOY) is the most common somatic change that
occurs in circulating white blood cells of older men. LOY in leukocytes is associated with …

Background Somatic genomic mosaicism occurs when somatic cells of the body display
different genotypes (Table 1), it has recently received increased attention because of its …

Benign & Pathological Chromosomal Imbalances systematically clarifies the disease
implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic …

Background Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the
most common abnormality in cancer. While certain aberrations, most commonly …

Multiple studies have demonstrated the utility of chromosomal microarray (CMA) testing to
identify clinically significant copy number alterations (CNAs) and copy-neutral loss-of …