Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Bone marrow (BM) analysis is required for morphological and genetic assessment in
patients evaluated for myelodysplastic neoplasms (MDS) and thus currently represents the …

Abstract Background Plasma cell neoplasms (PCNs) encompass a spectrum of disorders
including monoclonal gammopathy of undetermined significance, smoldering myeloma …

We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …

Chromosomal aberrations (CAs) in human peripheral blood lymphocytes (PBL) measured
with the conventional cytogenetic assay have been used for human biomonitoring of …

Numerical and structural chromosomal abnormalities are the hallmarks of cancer. Whereas
the structural chromosome aberrations got more substantial attention for cancer risk …

Benign & Pathological Chromosomal Imbalances systematically clarifies the disease
implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic …

Background Somatic genomic mosaicism occurs when somatic cells of the body display
different genotypes (Table 1), it has recently received increased attention because of its …

Background Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the
most common abnormality in cancer. While certain aberrations, most commonly …