[PDF][PDF] Increased pro-inflammatory activity and impairment of human monocyte differentiation induced by in vitro exposure to cigarette smoke

L Lerner, D Weiner, R Katz, AZ Reznick… - J Physiol …, 2009 - jpp.krakow.pl
Cigarette smoking (CS) is associated with a variety of human pathologies including
cardiovascular disease and cancer. Human monocytes are prevalent in oral and respiratory …

Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes

S Giebe, M Brux, A Hofmann, F Lowe… - … -European Journal of …, 2023 - Springer
Monocytes exhibiting a pro-inflammatory phenotype play a key role in adhesion and
development of atherosclerotic plaques. As an alternative to smoking, next-generation …

Cigarette smoke condensate upregulates the gene and protein expression of proinflammatory cytokines in human fibroblast-like synoviocyte line

M Shizu, Y Itoh, R Sunahara, S Chujo… - Journal of Interferon & …, 2007 - liebertpub.com
Rheumatoid arthritis (RA) is characterized by proliferation of synoviocytes that produce
proinflammatory cytokines, which are implicated in the pathogenesis of RA. When human …

Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro

F Yuan, P Dong, X Wang, X Fu, M Dai… - … and toxicologic pathology, 2013 - Elsevier
Cigarette smoke exposure is associated with increased risk of different disorders.
Immunological dysfunction especially in macrophages is one of important reasons in the …

[PDF][PDF] Cigarette smoke-induced NF-kappa B activation in human lymphocytes: the effect of low and high exposure to gas phase of cigarette smoke

E Hasnis, M Bar-Shai, Z Burbea… - Journal of Physiology …, 2007 - researchgate.net
Cigarette smoking is linked to various human disorders. Active and passive smokers suffer
from inflammatory diseases of lungs and airways. Smoking-dependent airway inflammation …

Macrophage depletion protects against cigarette smoke-induced inflammatory response in the mouse colon and lung

D Lim, W Kim, C Lee, H Bae, J Kim - Frontiers in physiology, 2018 - frontiersin.org
Cigarette smoke (CS) is considered as a major risk factor for pulmonary and intestinal
inflammation. CS leads to macrophage infiltration in the mucosae of the lung and colon …

Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kB activation

N Sugano, K Shimada, K Ito, S Murai - Biochemical and biophysical …, 1998 - Elsevier
Cigarette smoke is a major risk factor for lung cancer and respiratory infections. This
increased susceptibility may result from cigarette smoke-induced impairment of the immune …

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

K Karimi, H Sarir, E Mortaz, JJ Smit, H Hosseini… - Respiratory …, 2006 - Springer
Background The major risk factor for the development of COPD is cigarette smoking.
Smoking causes activation of resident cells and the recruitment of inflammatory cells into the …

Cigarette smoke induces proinflammatory cytokine release by activation of NF-κB and posttranslational modifications of histone deacetylase in macrophages

SR Yang, AS Chida, MR Bauter… - … of Physiology-Lung …, 2006 - journals.physiology.org
Cigarette smoke-mediated oxidative stress induces an inflammatory response in the lungs
by stimulating the release of proinflammatory cytokines. Chromatin remodeling due to …

Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance

MJ Walters, MJ Paul-Clark, SK McMaster, K Ito… - Molecular …, 2005 - ASPET
Smoking cigarettes is a major risk factor for the development of cardiovascular and
respiratory disease. Moreover, smoking-induced pathophysiology is often resistant to the …