Three types of early termination Of antidepressant Page 1 International Cliniai shphrol 093),
83536 Three types of early termination Of antidepressant drug treatment M Linden M …

Guidelines for antidepressant drug therapy recommend continuing treatment for several
months, even after recovery. Premature termination of medication is viewed as a significant …

The onset of action of antidepressant drugs was investigated on the basis of two
independent, multicenter, double-blind studies, comparing amitriptyline (N= 120) …

Because the value of antidepressants is hampered by their delay in onset of action,
considerable attention has been focused on developing a drug that acts more rapidly …

The belief in delayed antidepressant action has been encouraged by a confusion between
the concepts of full response and the appearance of improvement. Conventional trial …

The onset of activity of antidepressants is an aspect of their efficacy which is of practical as
well as theoretical importance. Using medline a review of the literature published since 1975 …

Published reports of antidepressants in clinical trials were reviewed by conducting a
literature search focusing on the time period between 1969 and 1994; 240 English …

There is no accepted definition of what constitutes onset of antidepressant effect, and this
limits evaluation of the validity of many comparative reports. In order to clarify the nature of …

Even after optimal treatment with and response to antidepressant medications during acute
treatment of major depressive disorder, residual symptoms are common. Patients with …

Background: For years, investigators have tried to determine the speed of onset of
antidepressant drugs. Claims that particular drugs may produce a faster response in patients …