[HTML][HTML] Relationship between human semen parameters and deoxyribonucleic acid damage assessed by the neutral comet assay

AT Trisini, NP Singh, SM Duty, R Hauser - Fertility and sterility, 2004 - Elsevier
OBJECTIVE: To explore the association between semen parameters and sperm DNA
damage. DESIGN: Cross-sectional. SETTING: Andrology clinic. PATIENT (S): Two hundred …

Sperm DNA damage output parameters measured by the alkaline Comet assay and their importance

L Simon, KI Aston, BR Emery, J Hotaling… - Andrologia, 2017 - Wiley Online Library
The alkaline Comet assay has shown high diagnostic value to determine male reproductive
health and prognostic ability to predict ART success. Here, spermatozoon was analysed in …

Sperm preparation: DNA damage by comet assay in normo-and teratozoospermics

L Ahmad, S Jalali, SA Shami, Z Akram - Archives of Andrology, 2007 - Taylor & Francis
The present study was carried out on semen samples of human fertile and infertile subjects,
teratozoospermics (TZs) and idiopathics (IDs), with neat semen and sperm prepared by …

Reliability of the comet assay in cryopreserved human sperm

SM Duty, NP Singh, L Ryan, Z Chen… - Human …, 2002 - academic.oup.com
BACKGROUND: Although the comet assay has potential value for measuring DNA damage
in large epidemiological human sperm studies, it is impractical to perform the assay daily on …

[HTML][HTML] Integrity of human sperm DNA assessed by the neutral comet assay and its relationship to semen parameters and clinical outcomes for the IVF-ET program

HJ Chi, DY Chung, SY Choi, JH Kim… - Clinical and …, 2011 - ncbi.nlm.nih.gov
Objective To explore potential relationships between sperm DNA integrity and both semen
parameters and clinical outcomes. Methods Semen analysis of 498 samples was performed …

Embryo quality and IVF treatment outcomes may correlate with different sperm comet assay parameters

M Tomsu, V Sharma, D Miller - Human Reproduction, 2002 - academic.oup.com
BACKGROUND: Standard semen parameters have proven poor at predicting the outcomes
of IVF treatment cycles. As recent studies suggest that the male genome may play an …

[HTML][HTML] Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success

L Simon, D Lutton, J McManus, SEM Lewis - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To evaluate sperm DNA fragmentation and semen parameters to diagnose
male factor infertility and predict pregnancy after IVF. DESIGN: Prospective study. SETTING …

Novel use of COMET parameters of sperm DNA damage may increase its utility to diagnose male infertility and predict live births following both IVF and ICSI

J Nicopoullos, A Vicens-Morton, SEM Lewis… - Human …, 2019 - academic.oup.com
Abstract STUDY QUESTION Do the Comet parameters of the proportions of sperm with low
or high DNA damage improve the power of the test in the diagnosis of male infertility and/or …

A two-tailed Comet assay for assessing DNA damage in spermatozoa

M Enciso, J Sarasa, A Agarwal, JL Fernández… - Reproductive …, 2009 - Elsevier
DNA fragmentation is considered an important parameter of semen quality, and of significant
value as a predictor of male fertility. Poor quality chromatin is closely associated with, and …

DNA integrity in human spermatozoa: relationships with semen quality

DS IRVINE, JP TWIGG, EL GORDON… - Journal of …, 2000 - Wiley Online Library
The literature contains conflicting evidence regarding the existence of DNA damage in
spermatozoa from infertile male patients. To examine this phenomenon, we have studied …