Present study deciphers preparation of co-crystals of lipophilic glipizide by using four
different acids, oxalic, malonic, stearic, and benzoic acids, in order to achieve enhanced …

Background: Glimepiride has limited aqueous solubility and majorly suffers from
bioavailability issues that eventually reduce the pharmacotherapeutic potentials of the …

The main focus of the present study was to explore co-crystallization technique to engineer
pharmaceutical co-crystals of poorly aqueous soluble drug-Gliclazide (GLZ) using different …

Aim: Glimepiride (Glmp) is an oral hypoglycemic drug used for the treatment of type 2
diabetes mellitus. It has low and unpredictable bioavailability that is mainly caused by its …

Background Cocrystallization is one of the crystal engineering strategies used to alter the
physicochemical properties of drugs that are poorly water-soluble. Gliclazide (GLZ), an …

In the present study various crystalline forms of glipizide were prepared in order to enhance
dissolution rate of glipizide and to evaluate the stability of developed forms. Four different …

Objective: Development of pharmaceutical co-crystals is an interesting area of research as
co-crystals are unique because they have the advantages of maintaining drug's intrinsic …

Objective: Cocrystallisation is a promising method in order to increase the solubility and
dissolution of poorly water-soluble drugs. The aim of this study was to prepare, formulate …

The solid-state diversity of active pharmaceutical ingredients can provide theoretical
guidance for the production and storage of drugs. In this study, three solid forms of glipizide …

Solubility is one of the physical properties of active substances that affect drug absorption
after dissolved in the gastrointestinal tract. Drugs with a limited aqueous solubility show low …