Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study

RJ Dawe, DA Bennett, JA Schneider, K Arfanakis - PloS one, 2011 - journals.plos.org
The volume of the hippocampus measured with structural magnetic resonance imaging
(MRI) is increasingly used as a biomarker for Alzheimer's disease (AD). However, the …

A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline

T Den Heijer, F Van der Lijn, PJ Koudstaal, A Hofman… - Brain, 2010 - academic.oup.com
Hippocampal atrophy is frequently observed on magnetic resonance images from patients
with Alzheimer's disease and persons with mild cognitive impairment. Even in asymptomatic …

Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia

CR Jack Jr, DW Dickson, JE Parisi, YC Xu, RH Cha… - Neurology, 2002 - AAN Enterprises
Objectives: To assess the diagnostic specificity of MRI-defined hippocampal atrophy for AD
among individuals with a variety of pathologically confirmed conditions associated with …

[HTML][HTML] Cognitive aging and the hippocampus in older adults

A O'Shea, RA Cohen, EC Porges, NR Nissim… - Frontiers in aging …, 2016 - frontiersin.org
The hippocampus is one of the most well studied structures in the human brain. While age-
related decline in hippocampal volume is well documented, most of our knowledge about …

Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space

MS Mega, GW Small, ML Xu, J Felix… - Psychosomatic …, 2002 - journals.lww.com
Objective The objective of this study is to demonstrate the assessment of hippocampal
atrophy within a standard brain atlas for persons with age-associated memory impairment …

Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation

A Convit, MJ De Leon, J Golomb, AE George… - Psychiatric …, 1993 - Springer
We evaluated three groups of elderly individuals who were carefully screened to rule out
clinically significant diseases that could affect cognition. They were matched for age and …

The impact of aging on subregions of the hippocampal complex in healthy adults

F Kurth, N Cherbuin, E Luders - Neuroimage, 2017 - Elsevier
The hippocampal complex, an anatomical composite of several subregions, is known to
decrease in size with increasing age. However, studies investigating which subregions are …

Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla

GB Frisoni, R Ganzola, E Canu, U Rüb, FB Pizzini… - Brain, 2008 - academic.oup.com
Histological studies have suggested differing involvement of the hippocampal subfields in
ageing and in Alzheimer's disease. The aim of this study was to assess in vivo local …

Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease

MJ de Leon, A Convit, S DeSanti… - International …, 1997 - cambridge.org
There is compelling evidence for the early involvement of the hippocampal formation in the
natural history of Alzheimer's disease (AD). The evidence comes from recent …

MRI of the hippocampus in Alzheimer's disease: sensitivity, specificity, and analysis of the incorrectly classified subjects

MP Laakso, H Soininen, K Partanen, M Lehtovirta… - Neurobiology of …, 1998 - Elsevier
In this study, magnetic resonance imaging (MRI) of the hippocampus for the diagnosis of
early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the …