Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study
The volume of the hippocampus measured with structural magnetic resonance imaging
(MRI) is increasingly used as a biomarker for Alzheimer's disease (AD). However, the …
(MRI) is increasingly used as a biomarker for Alzheimer's disease (AD). However, the …
A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline
T Den Heijer, F Van der Lijn, PJ Koudstaal, A Hofman… - Brain, 2010 - academic.oup.com
Hippocampal atrophy is frequently observed on magnetic resonance images from patients
with Alzheimer's disease and persons with mild cognitive impairment. Even in asymptomatic …
with Alzheimer's disease and persons with mild cognitive impairment. Even in asymptomatic …
Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia
CR Jack Jr, DW Dickson, JE Parisi, YC Xu, RH Cha… - Neurology, 2002 - AAN Enterprises
Objectives: To assess the diagnostic specificity of MRI-defined hippocampal atrophy for AD
among individuals with a variety of pathologically confirmed conditions associated with …
among individuals with a variety of pathologically confirmed conditions associated with …
[HTML][HTML] Cognitive aging and the hippocampus in older adults
The hippocampus is one of the most well studied structures in the human brain. While age-
related decline in hippocampal volume is well documented, most of our knowledge about …
related decline in hippocampal volume is well documented, most of our knowledge about …
Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space
MS Mega, GW Small, ML Xu, J Felix… - Psychosomatic …, 2002 - journals.lww.com
Objective The objective of this study is to demonstrate the assessment of hippocampal
atrophy within a standard brain atlas for persons with age-associated memory impairment …
atrophy within a standard brain atlas for persons with age-associated memory impairment …
Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation
A Convit, MJ De Leon, J Golomb, AE George… - Psychiatric …, 1993 - Springer
We evaluated three groups of elderly individuals who were carefully screened to rule out
clinically significant diseases that could affect cognition. They were matched for age and …
clinically significant diseases that could affect cognition. They were matched for age and …
The impact of aging on subregions of the hippocampal complex in healthy adults
The hippocampal complex, an anatomical composite of several subregions, is known to
decrease in size with increasing age. However, studies investigating which subregions are …
decrease in size with increasing age. However, studies investigating which subregions are …
Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla
GB Frisoni, R Ganzola, E Canu, U Rüb, FB Pizzini… - Brain, 2008 - academic.oup.com
Histological studies have suggested differing involvement of the hippocampal subfields in
ageing and in Alzheimer's disease. The aim of this study was to assess in vivo local …
ageing and in Alzheimer's disease. The aim of this study was to assess in vivo local …
Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease
MJ de Leon, A Convit, S DeSanti… - International …, 1997 - cambridge.org
There is compelling evidence for the early involvement of the hippocampal formation in the
natural history of Alzheimer's disease (AD). The evidence comes from recent …
natural history of Alzheimer's disease (AD). The evidence comes from recent …
MRI of the hippocampus in Alzheimer's disease: sensitivity, specificity, and analysis of the incorrectly classified subjects
MP Laakso, H Soininen, K Partanen, M Lehtovirta… - Neurobiology of …, 1998 - Elsevier
In this study, magnetic resonance imaging (MRI) of the hippocampus for the diagnosis of
early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the …
early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the …