Quantification of thonningianin a in rat plasma by liquid chromatography tandem mass spectrometry and its application to a pharmacokinetic study

Q Liu, C Li, P Zhao, J Li, Z Deng - Pharmaceutical Biology, 2021 - Taylor & Francis
Context Thonningianin A is an ellagitannin substance and displays multiple
pharmacological activities. Objective This study investigated the pharmacokinetic …

Comparative pharmacokinetics of acteoside from total glycoside extracted from leaves of Rehmannia and Dihuangye total glycoside capsule in normal and diabetic …

XX Dai, SL Su, HD Cai, DD Wei… - Biomedical …, 2017 - Wiley Online Library
Rehmannia glutinosa Libosch (RG), is officially listed in the Chinese Pharmacopoeia and is
widely used in China. In this paper, a sensitive and rapid ultra‐performance liquid …

Pharmacokinetic and Bioavailability Studies of Galgravin after Oral and Intravenous Administration to Rats Using HPLC‐MS/MS Method

L Zhao, S Wang, X Huang, Y Fan, Z Xue… - BioMed Research …, 2021 - Wiley Online Library
This paper presents a new high‐performance liquid chromatography tandem mass
spectrometry (HPLC‐MS/MS) method with a rapid analysis of 6 min to determine the …

Inhibition of the pro-inflammatory mediators in rat neutrophils by shanzhiside methyl ester and its acetyl derivative isolated from Barleria prionitis

BV Ghule, NR Kotagale, KS Patil - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance The aerial parts of Barleria prionitis Linn.(BP)(
Acanthaceae) plant has long been used to treat inflammatory disorders such as toothache …

A simple and sensitive HPLC–MS/MS method for quantification of eggmanone in rat plasma and its application to pharmacokinetics

C Xie, A Ramirez, Z Wang, MSS Chow, J Hao - Journal of Pharmaceutical …, 2018 - Elsevier
Abstract Allosteric phosphodiesterase 4 (PDE4) inhibitors are highly sought after due to their
important anti-inflammatory and anti-cancer therapeutic effects. We recently identified …

Sensitive analysis and pharmacokinetic study of the isomers paeoniflorin and albiflorin after oral administration of Total Glucosides Of White Paeony Capsule in rats

F Fei, H Yang, Y Peng, P Wang, S Wang, Y Zhao… - … of Chromatography B, 2016 - Elsevier
A sensitive and reliable method using liquid chromatography tandem mass spectrometry
(LC–MS/MS) was established for the simultaneous assay of paeoniflorin and albiflorin in bio …

Phytotherapeutic Activities of Sanguisorba officinalis and its Chemical Constituents: A Review

E Jang, KS Inn, YP Jang, KT Lee… - The American journal of …, 2018 - World Scientific
Sanguisorba officinalis Linne (S. officinalis, Rosaceae) has been used as a medicinal plant
for the treatment of burns, hematemesis, melena, intestinal infections, and dermatitis for a …

Pharmacokinetics of ganoderic acid D and its main metabolite by liquid chromatography–tandem mass spectrometry

CR Cheng, M Yang, SH Guan, XH Wu, XY Pang… - … of Chromatography B, 2013 - Elsevier
The present study aims to investigate the pharmacokinetics of ganoderic acid D (GD), a
representative active triterpenoid from Ganoderma lucidum. A sensitive and selective liquid …

Preclinical assessment of β-d-mannuronic acid (M2000) as a non-steroidal anti-inflammatory drug

MJ Fattahi, M Abdollahi… - …, 2015 - Taylor & Francis
Context: β-d-Mannuronic acid (M2000) has shown its therapeutic effects with the greatest
tolerability and efficacy in various experimental models such as experimental autoimmune …

[HTML][HTML] Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats …

S Liu, T Zhang, H Sun, L Lin, N Gao, W Wang, S Li… - Marine Drugs, 2021 - mdpi.com
dHG-5 (Mw 5.3 kD) is a depolymerized glycosaminoglycan from sea cucumber Holothuria
fuscopunctata. As a selective inhibitor of intrinsic Xase (iXase), preclinical study showed it …