Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy

AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh… - Seminars in Cancer …, 2022 - Elsevier
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …

Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …

Dendrimer as a promising nanocarrier for the delivery of doxorubicin as an anticancer therapeutics

V Singh, P Kesharwani - Journal of Biomaterials Science, Polymer …, 2021 - Taylor & Francis
Dendrimers are macromolecules with high-polymeric branching capable of undergoing
major modifications. These characteristics make them an efficient nanocarrier capable of …

Dendrimers for drug delivery

AM Caminade, CO Turrin - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
Due to their nanometric size, dendrimers have been considered as potentially suitable as
new vehicles for drug delivery since their infancy. The association of a dendrimer and a drug …

Dendrimers in gene delivery

C Dufès, IF Uchegbu, AG Schätzlein - Advanced drug delivery reviews, 2005 - Elsevier
Dendrimers have unique molecular architectures and properties that make them attractive
materials for the development of nanomedicines. Key properties such as defined …

Dendrimers in targeted drug delivery applications: A review of diseases and cancer

AK Mandal - International Journal of Polymeric Materials and …, 2021 - Taylor & Francis
Dendrimers in nanobiomedicine have attracted attention to overcome the biological barriers
because of their suitable characteristics such as nanosize, hyperbranching polymeric …

RETRACTED: Dendrimer nanocarriers as versatile vectors in gene delivery

T Dutta, NK Jain, NAJ McMillan, HS Parekh - … Nanotechnology, Biology and …, 2010 - Elsevier
The successful delivery of nucleic acids to particular target sites is the challenge that is
being addressed using a variety of viral and nonviral delivery systems, both of which have …

Recent advances in dendrimer-based nanovectors for tumor-targeted drug and gene delivery

P Kesharwani, AK Iyer - Drug discovery today, 2015 - Elsevier
Highlights•Dendrimers are nanovectors with well-defined architecture and tunable surface
characteristics.•Dendrimers can take advantage of passive and active tumor targeting for …