Many glycosyltransferase inhibitors in the literature are structurally derived from the donor or
acceptor substrate of the respective enzyme. A representative example is 2-naphthyl β-d …

The crystal structure of the catalytic domain of bovine β1, 4-galactosyltransferase (Gal-T1) co-
crystallized with UDP-Gal and MnCl2 has been solved at 2.8 Å resolution. The structure not …

Abstract β3-Galactosyltransferase (β3GalT) transfers a galactose from UDP-Gal to N-
acetylglucosamine (GlcNAc) with a β1, 3-linkage. To date, five members of the β3GalT family …

Biosynthetically, bovine N-acetylglucosainine β 1, 4-galacto-syltransferase (GalT) catalyses
the transfer of galactosyl residues from UDP-Gal to the 4-position of GlcNAc units, resulting …

β1, 4-Galactosyltransferase I (Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in the
presence of Mn 2+ ion. In the presence of α-lactalbumin (LA), the Gal acceptor specificity is …

Most glycosyltransferases, including B4GalT1 (EC 2.4. 1.38), are known to assemble into
enzyme homomers and functionally relevant heteromers in vivo. However, it remains …

Among glycosaminoglycan (GAG) biosynthetic enzymes, the human β1, 4-
galactosyltransferase 7 (hβ4GalT7) is characterized by its unique capacity to take over …

Galactosyltransferases are important enzymes for the extension of the glycan chains of
glycoproteins and glycolipids, and play critical roles in cell surface functions and in the …

抄録 ガラクトース転移酵素は糖転移酵素のファミリーの中で最も代表的なものである.
ガラクトース転移酵素は UDP-α-D-ガラクトースを供与体としてガラクトースを糖タンパク質 …

A β1, 3-galactosyltransferase (WbgO) was identified in Escherichia coli O55: H7. Its function
was confirmed by radioactive activity assay and structure analysis of the disaccharide …