β-1, 4-Galactosyltransferase-I (β4Gal-T1) transfers galactose from UDP-galactose to N-
acetylglucosamine (GlcNAc) residues of the branched N-linked oligosaccharide chains of …

Six β4-galactosyltransferase (β4GalT) genes have been cloned from mammalian sources.
We show that all six genes are expressed in the Gat− 2 line of Chinese hamster ovary cells …

Abstract The Galβ1→ 4GlcNAc structure is commonly found in the outer chain moieties of N-
and O-linked oligosaccharides, and in the oligosaccharides of lacto-series glycolipids. The …

Abstract Unlike classical β-1, 4-galactosyltransferase (β-1, 4-GalT I), β-1, 4-GalT V (formerly
IV*) has little activity towards 1 mM N-acetylglucosamine [Sato et al.(1998) Proc Natl Acad …

β-1, 4-galactosyltransferase-1, a housekeeping enzyme that functions in the synthesis of
glycoconjugates, has two flexible loops, one short and one long. Upon binding a metal ion …

A number of N-and C-terminal deletion and point mutants of bovine β-1, 4
galactosyltransferase (β-1, 4GT) were expressed in E. coli to determine the binding regions …

β1, 4-Galactosyltransferase I (GalT I) is one of the most extensively studied
glycosyltransferases. It is localized in the trans-Golgi compartment of most eukaryotic cells …

In order to assess the function of the different human UDP-Gal: GlcNAc β4-
galactosyltransferases, the cDNAs of two of them, β4-GalT I and β4-GalT V, were expressed …

The Galβ1→ 4 (SO 3−→ 6) GlcNAc moiety is present in various N-linked andO-linked
glycans including keratan sulfate and 6-sulfosialyl-Lewis X, an L-selectin ligand. We …

Bovine β-(1→ 4)-galactosyltransferase was assayed with a series of 5a-carba-sugars, ie,
sugar analogues in which the ring oxygen of pyranose is replaced by a methylene group …