ProcessingO-glycan core 1, Galβ1-3GalNAcα-R. Specificities of core 2, UDP-GlcNAc: Galβ1-3GalNAc-R(GlcNAc to GalNAc) β6-N-acetylglucosaminyltransferase and …
W Kuhns, V Rutz, H Paulsen, KL Matta, MA Baker… - Glycoconjugate …, 1993 - Springer
To elucidate control mechanisms of O-glycan biosynthesis in leukemia and to develop
biosynthetic inhibitors we have characterized core 2 UDP-GlcNAc: Galβ1-3GalNAc-R …
biosynthetic inhibitors we have characterized core 2 UDP-GlcNAc: Galβ1-3GalNAc-R …
Synthesis of 2′-O-substituted β-D-Gal-(1→ 4)-β-D-GlcNAc-1-0-Bn as specific acceptors for α-L-(1→ 3) fucosyltransferases
RK Jain, RD Locke, EV Chandrasekaran… - Bioorganic & medicinal …, 1992 - Elsevier
Abstract The synthesis of 2′-O-methyl lactosamine-β-OBn and 2′-O-α-L-fucopyranosyl
lactosamine-β-O-Bn were accomplished through the use of a key glycosyl donor, phenyl 3 …
lactosamine-β-O-Bn were accomplished through the use of a key glycosyl donor, phenyl 3 …
Stereoselective preparation of four 3-C-mannosylated d-and l-glucals from a single starting compound
Z Lövyova, K Parkan, L Kniežo - Tetrahedron, 2011 - Elsevier
The corresponding oxadiene, prepared from the starting perbenzylated α-d-
mannopyranosylethanal was subjected to stereoselective cycloaddition reactions with R and …
mannopyranosylethanal was subjected to stereoselective cycloaddition reactions with R and …
Structural Snapshots of α‐1, 3‐Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases
D Albesa‐Jové, MÁ Sainz‐Polo, A Marina… - Angewandte …, 2017 - Wiley Online Library
Glycosyltransferases (GTs) are a key family of enzymes that catalyze the synthesis of
glycosidic bonds in all living organisms. The reaction involves the transfer of a glycosyl …
glycosidic bonds in all living organisms. The reaction involves the transfer of a glycosyl …
[引用][C] Differing rates of galactosylation of homologous spacer-modified disaccharides are an indication for two separate GlcNAc binding-sites in galactosyltransferase
SC Ats, J Lehmann, S Petry - Carbohydrate research, 1994 - Elsevier
The biantennary N-linked core-heptasaccharide 1 is a natural acceptor for enzymic (1+ 4)-/3-
o-galactosylation, preferentially of the 3-linked antenna'. This site-specificity and the …
o-galactosylation, preferentially of the 3-linked antenna'. This site-specificity and the …
[HTML][HTML] Structural basis for the synthesis of the core 1 structure by C1GalT1
C1GalT1 is an essential inverting glycosyltransferase responsible for synthesizing the core 1
structure, a common precursor for mucin-type O-glycans found in many glycoproteins. To …
structure, a common precursor for mucin-type O-glycans found in many glycoproteins. To …
A coupled assay for UDP-GlcNAc: Galβ1-3GalNAc-R β1, 6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc)
A Datti, A Orlacchio, KA Siminovitch, JW Dennis - Analytical biochemistry, 1992 - Elsevier
UDP-GlcNAc: Galβ1-3GalNAc-R β1, 6-N-acetylglucosaminyltransferase (GlcNAc to
GalNAc)(ie, core 2 GlcNAc-T) is a developmentally regulated enzyme of the O-linked …
GalNAc)(ie, core 2 GlcNAc-T) is a developmentally regulated enzyme of the O-linked …
Glycosyltransferases in chemo-enzymatic synthesis of oligosaccharides
B Tefsen, I van Die - Glycosyltransferases: Methods and Protocols, 2013 - Springer
Many oligosaccharides are not commercially available, which limits studies focused on
elucidation of glycan functions; therefore chemo-enzymatic methods to synthesize them can …
elucidation of glycan functions; therefore chemo-enzymatic methods to synthesize them can …
Synthesis of four novel trisaccharides by induction of loose acceptor specificity in Galβ31→4 transferase (EC 2.4.1.22): Galp(β1→4)Glcp(X)Glc where X =β1→3: β1→ …
E Yoon, RA Laine - Glycobiology, 1992 - academic.oup.com
Abstract Development of tandem mass spectral methods for direct linkage determination in
oligosaccharides requires sets of trisaccharides differing only in one structural parameter. In …
oligosaccharides requires sets of trisaccharides differing only in one structural parameter. In …
β3-N-Acetylglucosaminyltransferase (iGnT)
M Fukuda - Handbook of Glycosyltransferases and Related Genes, 2002 - Springer
Abstract β3-N-Acetylglucosaminyrtransferase, i-extension enzyme (iGnT), is a
glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to Gal in the …
glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to Gal in the …