Aims and MethodTo assess and update the data on the use of St John's Wort as an
antidepressant. A Medline search was conducted for the period January 1985 to December …

Objective: The objective of this article is to review the current knowledge of the
pharmacology, sites of action, and therapeutic effectiveness of St. John's Wort. Method: The …

There is a moderate amount of evidence to suggest that St John's wort is better than placebo
in the short-term management of mild to moderate depressive illness, but there is increasing …

Objective: This study looks to compare the antidepressant efficacy and safety of a
standardized extract of St John's wort with both placebo and fluoxetine. Method: After a 1 …

ContextExtracts of St John's wort are widely used to treat depression. Although more than 2
dozen clinical trials have been conducted with St John's wort, most have significant flaws in …

Objective The primary purpose of this article is to review the existing literature concerning
the therapeutic uses, adverse effects, and possible drug interactions of St. John's wort …

Reports on a randomized, double-blind, placebo-controlled clinical trial conducted to study
the efficacy of St. John's wort (SJW) extract in patients with mild to moderate depression …

Background: A continuation study of an extract of St. John's wort (Hypericum perforatum) for
depression was performed in follow-up to an acute study that found no significant difference …

To address whether St John's wort is useful for the treatment of depression we attempted to
retrieve all English-language articles with data on the efficacy, safety, and availability of St …

ObjectiveExtracts of St. John's wort have been widely used in the treatment of depression.
Our aim was to review information related to the efficacy and safety of St. John's wort as an …