AD− 1 small molecule improves learning and memory function in scopolamine-induced amnesic mice model through regulation of CREB/BDNF and NF-κB/MAPK …
R Balakrishnan, JY Park, DY Cho, JY Ahn, DS Yoo… - Antioxidants, 2023 - mdpi.com
Cognitive decline and memory impairment induced by oxidative brain damage are the
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …
Chinese herbal extracts exert neuroprotective effect in Alzheimer's disease mouse through the dopaminergic synapse/apoptosis signaling pathway
Q Huang, C Zhang, S Qu, S Dong, Q Ma… - Frontiers in …, 2022 - frontiersin.org
Background: Alzheimer's disease (AD) as an age-related, irreversible neurodegenerative
disease, characterized by cognitive dysfunction, has become progressively serious with a …
disease, characterized by cognitive dysfunction, has become progressively serious with a …
Sodium tanshinone IIA sulfonate attenuates scopolamine‐induced cognitive dysfunctions via improving cholinergic system
QQ Xu, YJ Xu, C Yang, Y Tang, L Li… - BioMed research …, 2016 - Wiley Online Library
Sodium Tanshinone IIA sulfonate (STS) is a derivative of Tanshinone IIA (Tan IIA). Tan IIA
has been reported to possess neuroprotective effects against Alzheimer's disease (AD) …
has been reported to possess neuroprotective effects against Alzheimer's disease (AD) …
Danshensu attenuates scopolamine and amyloid-β-induced cognitive impairments through the activation of PKA-CREB signaling in mice
HJ Bae, K Sowndhararajan, HB Park, SY Kim… - Neurochemistry …, 2019 - Elsevier
Alzheimer's disease (AD) is an important chronic neurodegenerative disorder and is mainly
associated with cognitive dysfunction. At present, bioactive compounds from traditional …
associated with cognitive dysfunction. At present, bioactive compounds from traditional …
Melatonin rescue oxidative stress-mediated neuroinflammation/neurodegeneration and memory impairment in scopolamine-induced amnesia mice model
Cognitive decline and memory impairment induced by oxidative brain damage are the
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …
Friedelin attenuates neuronal dysfunction and memory impairment by inhibition of the activated JNK/NF-κB signalling pathway in scopolamine-induced mice model of …
Oxidative stress (OS) and c-Jun N-terminal kinase (JNK) are both key indicators implicated
in neuro-inflammatory signalling pathways and their respective neurodegenerative …
in neuro-inflammatory signalling pathways and their respective neurodegenerative …
Phytochemical allylguaiacol exerts a neuroprotective effect on hippocampal cells and ameliorates scopolamine-induced memory impairment in mice
HS Lim, BY Kim, YJ Kim, SJ Jeong - Behavioural Brain Research, 2018 - Elsevier
Allylguaiacol is a phytochemical occurring in various plants such as cloves, cinnamon, basil,
and nutmeg. Pharmacological effects of allylguaiacol include antimicrobial, anti …
and nutmeg. Pharmacological effects of allylguaiacol include antimicrobial, anti …
Analogous β-carboline alkaloids harmaline and harmine ameliorate scopolamine-induced cognition dysfunction by attenuating acetylcholinesterase activity, oxidative …
SP Li, YW Wang, SL Qi, YP Zhang, G Deng… - Frontiers in …, 2018 - frontiersin.org
The analogous β-carboline alkaloids, harmaline (HAL) and harmine (HAR), possess a
variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity …
variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity …
Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling …
B Lian, J Gu, C Zhang, Z Zou, M Yu, F Li, X Wu… - Metabolic Brain …, 2022 - Springer
Background Isofraxidin is a coumarin compound mainly isolated from several traditional and
functional edible plants beneficial for neurodegenerative diseases, including Sarcandra …
functional edible plants beneficial for neurodegenerative diseases, including Sarcandra …
Neuroprotective effect of Saroglitazar on scopolamine-induced Alzheimer's in rats: insights into the underlying mechanisms
G Sandeep Ganesh, P Konduri, AS Kolusu… - ACS Chemical …, 2023 - ACS Publications
Alzheimer's disease (AD) is one of the most prevalent and progressive neurodegenerative
disorders, hallmarked by increased amyloid-β deposition and enhanced oxidative load in …
disorders, hallmarked by increased amyloid-β deposition and enhanced oxidative load in …
相关搜索
- creb bdnf small molecule
- creb bdnf nf κb
- small molecule nf κb
- signaling pathway bdnf creb
- memory impairments bdnf creb
- memory impairment nf κb
- signaling pathway memory impairments
- signalling pathway nf κb
- signaling in mice pka creb
- signaling in mice cognitive impairments
- protective effects bdnf creb
- neuronal dysfunction nf κb
- signaling pathway protective effects
- signaling in mice amyloid β
- signaling pathway creb erk
- memory impairments creb erk