Chromosome 4q31 locus in COPD is also associated with lung cancer
RP Young, CF Whittington, RJ Hopkins… - European …, 2010 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is the single greatest risk factor for lung
cancer in smokers and is found in 50–90% of lung cancer cases. The link between COPD …
cancer in smokers and is found in 50–90% of lung cancer cases. The link between COPD …
[HTML][HTML] Oxidative stress-based therapeutics in COPD
PJ Barnes - Redox biology, 2020 - Elsevier
Oxidative stress is a major driving mechanism in the pathogenesis of COPD. There is
increased oxidative stress in the lungs of COPD patients due to exogenous oxidants in …
increased oxidative stress in the lungs of COPD patients due to exogenous oxidants in …
COPD, emphysema and the onset of lung cancer. A systematic review
C Mouronte-Roibas, V Leiro-Fernandez… - Cancer letters, 2016 - Elsevier
Abstract Chronic Obstructive Pulmonary Disease (COPD) and emphysema have been
described as possible risk factors for lung cancer. We aim to assess the relationship …
described as possible risk factors for lung cancer. We aim to assess the relationship …
[HTML][HTML] Oxidative stress in COPD: sources, markers, and potential mechanisms
AJA McGuinness, E Sapey - Journal of clinical medicine, 2017 - mdpi.com
Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …
Impact of COPD on prognosis of lung cancer: from a perspective on disease heterogeneity
W Wang, S Dou, W Dong, M Xie, L Cui… - … journal of chronic …, 2018 - Taylor & Francis
Background COPD is an important comorbidity of lung cancer, but the impact of COPD on
the outcomes of lung cancer remains uncertain. Because both COPD and lung cancer are …
the outcomes of lung cancer remains uncertain. Because both COPD and lung cancer are …
Epidemiology of COPD
C Raherison, PO Girodet - European Respiratory Review, 2009 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is responsible for early mortality, high death
rates and significant cost to health systems. The projection for 2020 indicates that COPD will …
rates and significant cost to health systems. The projection for 2020 indicates that COPD will …
[HTML][HTML] Inflammation in chronic obstructive pulmonary disease and its role in cardiovascular disease and lung cancer
PT King - Clinical and translational medicine, 2015 - Springer
Chronic obstructive pulmonary disease (COPD) is characterized by lung inflammation that
persists after smoking cessation. This inflammation is heterogeneous but the key …
persists after smoking cessation. This inflammation is heterogeneous but the key …
Smoking and lung cancer: the role of inflammation
T Walser, X Cui, J Yanagawa, JM Lee… - Proceedings of the …, 2008 - atsjournals.org
Worldwide over 1 million people die due to lung cancer each year. It is estimated that
cigarette smoking explains almost 90% of lung cancer risk in men and 70 to 80% in women …
cigarette smoking explains almost 90% of lung cancer risk in men and 70 to 80% in women …
[HTML][HTML] Genetic susceptibility to lung cancer and co-morbidities
IA Yang, JW Holloway, KM Fong - Journal of thoracic disease, 2013 - ncbi.nlm.nih.gov
Lung cancer is a leading cause of cancer death and disease burden in many countries.
Understanding of the biological pathways involved in lung cancer aetiology is required to …
Understanding of the biological pathways involved in lung cancer aetiology is required to …