Human genetic studies have long been vastly Eurocentric, raising a key question about the
generalizability of these study findings to other populations. Because humans originated in …

The genomic architecture of African populations is poorly understood and there is
considerable variation between ethno-linguistic groups. Genome-wide approaches have …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

The continent of Africa is the source of all anatomically modern humans that dispersed
across the planet during the past 100,000 years. As such, African populations are …

Due to its long genetic evolutionary history, Africans exhibit more genetic variation than any
other population in the world. Their genetic diversity further lends itself to subdivisions of …

Because modern humans originated in Africa and have adapted to diverse environments,
African populations have high levels of genetic and phenotypic diversity. Thus, genomic …

A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …

Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

Genetic variation and susceptibility to disease are shaped by human demographic history
and adaptation. We can now study the genomes of extant Africans and uncover traces of …

Human genetics has emerged as one of the most dynamic areas of biology, with a
broadening societal impact. In this review, we discuss recent achievements, ongoing efforts …