抄録 ガラクトース転移酵素は糖転移酵素のファミリーの中で最も代表的なものである.
ガラクトース転移酵素は UDP-α-D-ガラクトースを供与体としてガラクトースを糖タンパク質 …

sulfate modified N-acetylglucosamine (6-sulfo-GlcNAc) is often found as part of many
biologically important carbohydrate epitopes such as 6-sulfo-Le X. In these epitopes, the 6 …

Glycosyltransferases (GTs) are a key family of enzymes that catalyze the synthesis of
glycosidic bonds in all living organisms. The reaction involves the transfer of a glycosyl …

The β-1, 4-galactosyltransferase 7 (β4GalT7) enzyme is involved in proteoglycan synthesis.
In the presence of a manganese ion, it transfers galactose from UDP-galactose to xylose on …

Abbreviations used: gal-T, galactosyltransferase; MEM. minimal essential medium; PBS,
phosphate-buffered saline; PMSF, phenylmethanesulphonylfluoride; SSEA, stage-specific …

β-1, 4-Galactosyltransferase I (β4Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in
the presence of Mn2+ ion (Gal-T activity) and also transfers Glc from UDP-Glc to GlcNAc (Glc …

Glycosyltransferases (GTs) are responsible for the biosynthesis of glycans, the most
abundant organic molecules in nature. Their biological relevance makes necessary the …

The catalytic domain of bovine α1→ 3-galactosyltransferase (α3GalT), residues 80–368,
have been cloned and expressed, in Escherichia coli. Using a sequential purification …

The crystal structure of the catalytic domain of bovine β1, 4-galactosyltransferase (Gal-T1) co-
crystallized with UDP-Gal and MnCl2 has been solved at 2.8 Å resolution. The structure not …

β1, 4-Galactosyltransferase I (GalT I) is one of the most extensively studied
glycosyltransferases. It is localized in the trans-Golgi compartment of most eukaryotic cells …