Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's and Parkinson's diseases as druggable targets through …
Microorganisms in human gastrointestinal tract have profound influence on the
transformation of food into metabolites which can impact human health. Along with playing …
transformation of food into metabolites which can impact human health. Along with playing …
Network pharmacological evaluation of Withania somnifera bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
Neurodegenerative disorders are illnesses that are responsible for neuronal cell death and
resulting in lifelong cognitive problems. Due to their unclear mechanism, there are no …
resulting in lifelong cognitive problems. Due to their unclear mechanism, there are no …
Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid …
From last decade, there has been progressive improvement in computational drug
designing. Several diseases are being cured from different plant extracts and products …
designing. Several diseases are being cured from different plant extracts and products …
Withanolides from Withania somnifera as an immunity booster and their therapeutic options against COVID-19
P Khanal, R Chikhale, YN Dey, I Pasha… - Journal of …, 2022 - Taylor & Francis
Traditionally, Withania somnifera is widely used as an immune booster, anti-viral, and for
multiple medicinal purposes. The present study investigated the withanolides as an immune …
multiple medicinal purposes. The present study investigated the withanolides as an immune …
Network pharmacology of Withania somnifera against stress associated neurodegenerative diseases
T Duyu, P Khanal, YN Dey, SK Jha - Advances in Traditional Medicine, 2021 - Springer
Withania somnifera is a Rasayana of the Ayurvedic system of medicine that is widely used to
treat stress-related neurological disorders. Although its anti-stress activity is reported in …
treat stress-related neurological disorders. Although its anti-stress activity is reported in …
[HTML][HTML] A Multi-Target mechanism of Withania somnifera bioactive compounds in autism spectrum disorder (ASD) Treatment: Network pharmacology, molecular …
SM Alqahtani - Arabian Journal of Chemistry, 2024 - Elsevier
Autism spectrum disorder (ASD) is a developmental disorder resulting from variations in
brain structure and function. Individuals with ASD often experience challenges in …
brain structure and function. Individuals with ASD often experience challenges in …
Identification of potential inhibitors of PARP-1, a regulator of caspase-independent cell death pathway, from Withania somnifera phytochemicals for combating neurotoxicity: A …
S Mukherjee, G Kumar, R Patnaik - Journal of Theoretical and …, 2017 - World Scientific
Poly (ADP-ribose) polymerase-1 (PARP-1) reverses DNA damage by repairing DNA nicks
and breaks in the normal cellular environment. However, during abnormal conditions like …
and breaks in the normal cellular environment. However, during abnormal conditions like …
In-silico validation of novel therapeutic activities of withaferin a using molecular docking and dynamics studies
R Surya Ulhas, A Malaviya - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Withaferin A is a bioactive molecule of W. somnifera. We access its efficacy against various
target proteins associated with Cancer, Type-II Diabetes and hypercholesterolemia using …
target proteins associated with Cancer, Type-II Diabetes and hypercholesterolemia using …
In-silico studies of phytoconstituents of Bacopa monnieri and Centella asiatica with crystal structure of myelin oligodendrocyte glycoprotein against primary …
There is a rapid spread of Multiple Sclerosis disorder across the globe. There are around 2.8
million cases of Multiple Sclerosis in the world; among them, 1 million are just present in the …
million cases of Multiple Sclerosis in the world; among them, 1 million are just present in the …
Analysis of medicinal and therapeutic potential of Withania somnifera derivatives against COVID-19
SZ Gheshlaghi, E Nakhaei, A Ebrahimi… - Journal of …, 2023 - Taylor & Francis
Apart from chemical and allopathic drugs, several medicinal plants contain phytochemicals
that are potentially useful to counter the COVID-19 pandemic. Withania somnifera …
that are potentially useful to counter the COVID-19 pandemic. Withania somnifera …
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