Desirable properties such as hypoimmunogenicity, multipotency, and robust self-
renewability have made adult stem cells an attractive cell source in regenerative medicine.[1 …

As our population ages, there is a greater need for a suitable supply of engineered tissues to
address a range of debilitating ailments. Stem cell based therapies are envisioned to meet …

The potential of stem cells in clinics and as a diagnostic tool is still largely unmet, partially
due to a lack of in vitro models that efficiently mimic the in vivo stem cell microenvironment …

Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …

During embryogenesis and tissue maintenance and repair in an adult organism, a myriad of
stem cells are regulated by their surrounding extracellular matrix (ECM) enriched with …

New fabrication technologies and, in particular, new nanotechnologies have provided
biomaterial and biomedical scientists with enormous possibilities when designing …

The development of homogenously nano-patterned chemically modified surfaces that can
be used to initiate a cellular response, particularly stem cell differentiation, in a highly …

As stem cells are a cornerstone of regenerative medicine, research efforts have been
extensively focused on controlling their self-renewal and differentiation. It is well-known that …

Stem cells possess unique abilities as they can renew themselves for extended periods of
time and have the capacity to differentiate into a variety of lineages. They hold promise for …

The development of biomedical devices and reconstruction of functional ex vivo tissues
often requires the need to fabricate biomimetic surfaces with features of sub‐micrometer …