Advances in Therapeutics to Alleviate Cognitive Decline and Neuropsychiatric Symptoms of Alzheimer's Disease

J Li, A Haj Ebrahimi, AB Ali - International Journal of Molecular Sciences, 2024 - mdpi.com
Dementia exists as a 'progressive clinical syndrome of deteriorating mental function
significant enough to interfere with activities of daily living', with the most prevalent type of …

A Recent Update on Pathophysiology and Therapeutic Interventions of Alzheimer's Disease

M Kashif, P Sivaprakasam, P Vijendra… - Current …, 2023 - ingentaconnect.com
Aim: Alzheimer's disease (AD) has been identified as a progressive brain disorder
associated with memory dysfunction and the accumulation of β-amyloid plaques and …

[HTML][HTML] Alzheimer's disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

AR Monteiro, DJ Barbosa, F Remião, R Silva - Biochemical Pharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases that
affect millions of people worldwide, with both prevalence and incidence increasing with age …

Impact of new drugs for therapeutic intervention in Alzheimer's disease

J Olloquequi, M Ettcheto, A Cano, E Sanchez-López… - 2022 - repositorio.uautonoma.cl
The increases in population ageing and growth are leading to a boosting in the number of
people living with dementia, Alzheimer's disease (AD) being the most common cause. In …

[HTML][HTML] Overview of therapeutic targets in management of dementia

R Malik, S Kalra, S Bhatia, A Al Harrasi, G Singh… - Biomedicine & …, 2022 - Elsevier
Dementia is defined as a gradual cognitive impairment that interferes with everyday tasks,
and is a leading cause of dependency, disability, and mortality. According to the current …

Novel approaches for the treatment of Alzheimer's and Parkinson's disease

M Van Bulck, A Sierra-Magro, J Alarcon-Gil… - International journal of …, 2019 - mdpi.com
Neurodegenerative disorders affect around one billion people worldwide. They can arise
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …

Therapeutic targeting strategies for early-to late-staged Alzheimer's disease

YJ Kang, YN Diep, M Tran, H Cho - International Journal of Molecular …, 2020 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia, typically showing
progressive neurodegeneration in aging brains. The key signatures of the AD progression …

[图书][B] Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

GM Ashraf, A Alexiou - 2019 - Springer
Alzheimer's disease (AD) is still a hardly curable disease with several symptoms of
behavioral and cognitive impairments. Besides the altered protein levels and the side effects …

Molecular mechanisms of emerging therapeutic targets in Alzheimer's disease: a systematic review

T Premkumar, S Sajitha Lulu - Neurochemical Journal, 2022 - Springer
Alzheimer's disease (AD) is a severe cognitive impairment considered to be the leading
cause of dementia worldwide. The pathophysiology includes extracellular accumulation of …

Neurodegenerative pathways in Alzheimer's disease: a review

AK Ramachandran, S Das, A Joseph… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …