ABSTRACT Introduction: GMDP (glucosaminyl-muramyl-dipeptide), a synthetic analog of the
peptidoglycan fragment of the bacterial cell wall, is an active component of the …

Abstract GMDP (glucosoaminyl‐muramyl‐dipeptide), a synthetic analog of the
peptidoglycan fragment of the bacterial cell wall, is an active component of the …

The analysis of the clinical application effectiveness of the drug Liсopid (the substance is
glucosaminylmuramyldipeptide–GMDP), is discussed. Many years of experience using the …

Introduction. For the determination of peptide-based drugs the reverse phase HPLC method
with a gradient elution mode is widely used. Among the published works no validated …

Muramyl dipeptide (MDP) is the smallest bacterial cell wall peptidoglycan component having
immunomodulatory activity. In an attempt to obtain MDP derivatives with improved and better …

Numerous non‐toxic peptidoglycan fragments of low molecular weight represent an
important group of immunomodulators, and antitumor and antiviral drugs. They were …

Peptidoglycan occurs naturally in cell wall structures of almost all types of bacteria. Muramyl
dipeptide (MDP) is a fragment of peptidoglycan, which consists of N-acetylmuramic acid that …

In this study flow cytometry was used to show that macrophages were the major population
of murine peritoneal exudate cells (MPEC), increasing la expression upon treatment with N …

A preliminary study has shown that 3, 8‐Di‐O‐methylellagic acid 2‐O‐glucoside (DMAG), an
ellagic tannin from Sanguisorba officinalis L., has the potential in relieving …

Bacterial peptidoglycan and its muropeptide derivatives potently activate mammalian innate
immune system and are promising immunomodulators and vaccine adjuvants. However …