Summary and Conclusions Depending on the dose size and solubility characteristics of low
solubility drugs, a meaningful and discriminatory power of dissolution rate testing can be …

In this study, it was shown that the incorporation of superdisintegrants in solid dispersion
tablets containing a high drug load can strongly enhance the dissolution rate of the highly …

The ability of in vitro biorelevant dissolution tests to predict the in vivo performance of
nanosized fenofibrate (Lipidil 145 ONE®) and microsized fenofibrate (Lipidil–Ter®) was …

In this study, solid dispersion systems of the sparingly water soluble drug, fenofibrate, in
PEG 6000 and PVP were prepared and characterized. The effect of particle size of solid …

Purpose. The dissolution behavior of two commercially availableglibenclamide formulations
was tested in various media. The aim of thestudy was to investigate whether the use of …

Fenofibrate is a lipid lowering drug used in the treatment of hyperlipidemia, which is not
soluble in water and lower absorption in gastric fluid. In order to improve the solubility and …

The solubility of fenofibrate in pH 6.8 McIlvaine buffers containing varying concentrations of
sodium lauryl sulfate was determined. The dissolution behavior of fenofibrate was also …

Several techniques were compared for improving the dissolution of fenofibrate, a poorly
soluble drug. Particle size reduction was realized by jet milling (micronization; cogrinding …

The aim of the current study was to evaluate a dynamic dissolution-/permeation-system for
prediction of gastrointestinal and absorption-behavior of two commercial fenofibrate …

The development of a meaningful dissolution procedure for drug products with limited water
solubility has been a challenge to both the pharmaceutical industry and the agencies that …