The objective of this study was to assess the effect of a novel regimen of antibiotic
prophylaxis on the incidence of lower respiratory tract infection in patients requiring …

In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on
quantitative colonization and respiratory infections were studied in intubated patients with an …

A novel regimen of selective decontamination (SDD) with initial systemic cefotaxime
prevented bacterial colonization of the oropharynx and stomach in mechanically ventilated …

Secondary pneumonia in patients requiring mechanical ventilation has a high morbidity and
mortality. Diagnosis is difficult and treatment failure common; therefore, preventive measures …

We report the results of a prophylactic regime designed to prevent endogenous colonization
and infection of the lower airways by Gram-negative bacilli. The 27 study patients spent an …

Nosocomial pneumonias, especially in ventilated patients, are a continuing problem in
modern medicine. Pathogens most commonly involved with these pneumonias are …

Objective: At least 7 meta-analyses (MA) have been published since 1991 on the
effectiveness of antibiotic prophylaxis in Intensive care units (ICU) patients, but controversy …

The high prevalence of nosocomial infections in critically ill ICU patients is associated with
high antibiotic consumption. Besides its economic impact, there is the constant threat of …

Generally, reduction of colonization and infection with potentially pathogenic
microorganisms in intensive care units (ICU) is attempted by a combination of antimicrobial …

In a prospective randomized study to determine whether prevention of colonization of Gram-
negative bacteria results in prevention of Gram-negative bacterial infections, 96 intensive …