[HTML][HTML] Human natural killer cells and other innate lymphoid cells in cancer: Friends or foes?

P Vacca, E Munari, N Tumino, F Moretta, G Pietra… - Immunology …, 2018 - Elsevier
Innate lymphoid cells (ILC) including NK cells (cytotoxic) and the recently identified “helper”
ILC1, ILC2 and ILC3, play an important role in innate defenses against pathogens. Notably …

[HTML][HTML] Innate lymphoid cells in tumor immunity

JJP Van Beek, AWJ Martens, G Bakdash, IJM De Vries - Biomedicines, 2016 - mdpi.com
Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not
possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue …

Natural killer cells and type 1 innate lymphoid cells in cancer

N Lopes, E Vivier, E Narni-Mancinelli - Seminars in Immunology, 2023 - Elsevier
Innate lymphoid cells (ILCs) are a group of innate lymphocytes that do not express RAG-
dependent rearranged antigen-specific cell surface receptors. ILCs are classified into five …

Targeting natural killer cells in solid tumors

G Habif, A Crinier, P André, E Vivier… - Cellular & molecular …, 2019 - nature.com
Natural killer (NK) cells are innate lymphoid cells endowed with cytolytic activity and a
capacity to secrete cytokines and chemokines. Several lines of evidence suggest that NK …

Natural killer cells and other innate lymphoid cells in cancer

L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
Immuno-oncology is an emerging field that has revolutionized cancer treatment. Most
immunomodulatory strategies focus on enhancing T cell responses, but there has been a …

Roles of cytotoxic and helper innate lymphoid cells in cancer

C Guillerey - Mammalian genome, 2018 - Springer
Natural killer (NK) cells have long been recognized for their anti-cancer activity and are now
included in the large family of innate lymphoid cells (ILCs). The discovery of new ILC …

[HTML][HTML] The role of ILC subsets in cancer

M Bruchard, H Spits - Seminars in immunology, 2022 - Elsevier
The family of innate lymphoid cells (ILCs) are composed of five canonical subsets, NK cells,
ILC1, ILC2, ILC3 and Lymphoid tissue inducer cells. ILCs have important functions in early …

[HTML][HTML] Role of distinct natural killer cell subsets in anticancer response

H Stabile, C Fionda, A Gismondi, A Santoni - Frontiers in immunology, 2017 - frontiersin.org
Natural killer (NK) cells, the prototypic member of innate lymphoid cells, are important
effectors of anticancer immune response. These cells can survey and control tumor initiation …

[HTML][HTML] The dual role of innate lymphoid and natural killer cells in cancer. From phenotype to single-cell transcriptomics, functions and clinical uses

S Roma, L Carpen, A Raveane, F Bertolini - Cancers, 2021 - mdpi.com
Simple Summary Innate lymphoid cells (ILCs), a family of innate immune cells including
natural killers (NKs), play a multitude of roles in first-line cancer control, in escape from …

Natural killer cells in innate immunity and cancer

B Becknell, MA Caligiuri - Journal of immunotherapy, 2008 - journals.lww.com
In humans, natural killer (NK) cells are CD56+ CD3− lymphocytes that constitute 1
component of the innate immune system. NK cells were first described functionally by virtue …