Pancreatic cancer is characterized by an often dramatic outcome (five year survival< 5%)
related to a late diagnosis and a lack of efficient therapy. Therefore, clinicians desperately …

Introduction: Pancreatic cancer (PC) is characterized by mucin overexpression. MUC4 is the
most differentially overexpressed membrane-bound mucin that plays a functional role in …

Pancreatic ductal adenocarcinoma (PDA) is the 4 th leading cause of cancer-related deaths
in the US. An understanding of the molecular pathogenesis of PDA is of utmost importance …

Mucins are members of an expanding family of large multifunctional glycoproteins.
Pancreatic mucins have important biological functions, including the protection, lubrication …

Pancreatic cancer (PC) is the 4th leading cause of cancer-related mortalities in the United
States with an estimated 56,770 new cases and more than 45,750 deaths in 2019 [1] …

Introduction: Pancreatic cancer is the third leading cause of cancer-related deaths in the US
and 95% of pancreatic cancers are Pancreatic Ductal Adenocarcinomas (PDACs) …

The third leading cause of cancer-related deaths in the United States is pancreatic cancer,
more than 95% of which is pancreatic ductal adenocarcinoma (PDA). The incidence rate of …

Physicians and research scientists have been working “hand in hand” to find every possible
way to prevent and treat patients from the deadly disease “cancer” since the early 1900. The …

MUC1, a tumor associated glycoprotein over-expressed in 95% of pancreatic cancers, has
been shown to be associated with a worse prognosis. The objective of this study was to …

742 Background: Pancreatic adenocarcinoma (PC) is a highly aggressive cancer with a 5-
year survival rate around 9% with majority of patients diagnosed at advanced stage. Prior …