Genomic and post-genomic biological research has provided fine-grain insights into the
molecular processes of life, but also threatens to drown biomedical researchers in data …

Abstract The Macromolecular Structure Database (MSD) group (http://www. ebi. ac. uk/msd/)
continues to enhance the quality and consistency of macromolecular structure data in the …

The mission of the European Bioinformatics Institute (EBI), an outstation of the European
Molecular Biology Laboratory (EMBL) in Heidelberg, is to ensure that the growing body of …

The origins of bioinformatics, both as a term and as a discipline, are difficult to pinpoint. The
expression was used as early as 1977 by Dutch theoretical biologist Paulien Hogeweg …

Data resources at the European Bioinformatics Institute (EMBL-EBI, https://www. ebi. ac. uk/)
archive, organize and provide added-value analysis of research data produced around the …

Motivation: The efficiency of bioinformatics programmers can be greatly increased through
the provision of ready-made software components that can be rapidly combined, with …

Molecular Biology has been at the heart of the 'big data'revolution from its very beginning,
and the need for access to biological data is a common thread running from the 1965 …

The wide uptake of next-generation sequencing and other ultra-high throughput
technologies by life scientists with a diverse range of interests, spanning fundamental …

Life science data integration and interoperability is one of the most challenging problems
facing bioinformatics today. In the current age of the life sciences, investigators have to …

Future generations may be able to determine whether the sequencing of the human genome
in 2001 indeed led to a paradigm shift in biology and biomedicine as some predicted, or …