Functional oocytes are produced through complex molecular and cellular processes. In
particular, the contribution of post-transcriptional gene regulation mediated by RNA-binding …

Translational control of gene expression is an important component of the regulation of
cellular differentiation and development. To elucidate the function of the 3′ untranslated …

Dax-1, a member of the nuclear hormone receptor superfamily of transcription factors, is
known to be involved in gonadal development in mammals. To date, Dax-1 has only been …

During differentiation of the male gamete, there is a massive remodelling in the shape and
architecture of all the cells in the seminiferous epithelium. The cytoskeleton, as well as many …

Abstract DDX3X, the functional X homologue of the major AZFa gene, DDX3Y, belongs to
the highly conserved PL10-subfamily of DEAD-box RNA helicase genes which are …

To investigate the germ cell specification in urodeles, we cloned a DAZ-like sequence from
the Japanese newt Cynops pyrrhogaster, Cydazl, and raised antibodies specific to Cydazl …

Abstract DAX-1, an X-linked member of the orphan nuclear receptor superfamily of
transcription factors, plays a key role in sex determination and gonadal differentiation. Dax1 …

Nkd1 is an antagonist of the canonical Wnt/β-catenin signaling pathway. The EF-hand motif
of Nkd1 is required for its inhibitory function. Early studies suggested that Nkd1 might play …

By hybridizing human adult testis cDNA microarrays with human adult and embryo testis
cDNA probes, we identified a novel human testis gene, NYD-SP15. NYD-SP15 expression …

Dead end is a vertebrate-specific RNA-binding protein implicated in germ cell development.
We have previously shown that mouse Dead end1 (DND1) is expressed in male embryonic …