Gene therapy is a promising treatment modality that is being explored for several inherited
disorders. Multiple human gene therapy clinical trials are currently ongoing, but few are …

The advent of optogenetics has ushered in a new era in neuroscience where spatiotemporal
control of neurons is possible through light application. These tools used to study neural …

For individuals with severe to profound hearing loss resulting from irreversibly damaged hair
cells, cochlear implants can be used to restore hearing by delivering electrical stimulation …

An estimated 466 million people suffer from hearing loss worldwide. Sensorineural hearing
loss is characterized by degeneration of key structures of the sensory pathway in the …

Genetic hearing loss crosses almost all the categories of hearing loss which includes the
following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital …

Objective: To provide an overview of biotechnology and pharmaceutical companies active in
the field of inner ear and central hearing disorders and their therapeutic approaches …

Three technologies have emerged as therapies to restore light sensing to profoundly blind
patients suffering from late-stage retinal degenerations:(1) retinal prosthetics,(2) …

Understanding how different kinds of neuron in the brain work together to implement
sensations, feelings, thoughts, and movements, and how deficits in specific kinds of neuron …

Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

Optogenetics provides a means to dissect the organization and function of neural circuits.
Optogenetics also offers the translational promise of restoring sensation, enabling …