Optogenetics provides a means to dissect the organization and function of neural circuits.
Optogenetics also offers the translational promise of restoring sensation, enabling …

Hearing loss stands as the most prevalent sensory deficit among humans, posing a
significant global health challenge. Projections indicate that by 2050, approximately 10% of …

Over the last few years, huge progress has been made with regard to the understanding of
molecular mechanisms underlying the pathogenesis of neurodegenerative diseases of the …

Vision, olfaction, hearing, and balance are mediated by receptors that reside in specialized
sensory epithelial organs. Age-related degeneration of the photoreceptors in the retina and …

Optogenetics is the use of genetically encoded light-activated proteins to manipulate cells in
a minimally invasive way using light. The most prominent example is channelrhodopsin-2 …

Optogenetics offers promise for dissecting the complex neural circuits of the spinal cord and
peripheral nervous system and has therapeutic potential for addressing unmet clinical …

Since the successful introduction of exogenous photosensitive proteins, channelrhodopsin,
to neurons, optogenetics has enabled substantial understanding of profound brain function …

Optogenetics is an innovative technique for optical control of cells. This field has exploded
over the past decade or so and has given rise to great advances in neuroscience. A variety …

Noise, chemicals and genetic defects are all common causes of irreversible hearing loss,
which at present have no cure. Gene therapy may soon be utilized in both the protection and …

The field of optogenetics uses genetically encoded, lightresponsive proteins to control
physiological processes. This technology has been hailed as the one of the ten big ideas in …