β-1, 4-Galactosyltransferase-I (β4Gal-T1) transfers galactose from UDP-galactose to N-
acetylglucosamine (GlcNAc) residues of the branched N-linked oligosaccharide chains of …

N-Acetyllactosamine is the most prevalent disaccharide moiety in the glycans on the surface
of mammalian cells and often found as repeat units in the linear and branched …

β1, 4-Galactosyltransferase I (Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in the
presence of Mn 2+ ion. In the presence of α-lactalbumin (LA), the Gal acceptor specificity is …

To understand the contribution of β1, 4-galactosyltransferase (β4Gal-T)-1 to galactosylation
in vivo, N-glycans of hepatic membrane glycoproteins and plasma glycoproteins from β4Gal …

Cell surface glycans play important cellular functions and are synthesized by
glycosyltransferases. Structure and function studies show that the donor sugar specificity of …

β-1, 4-Galactosyltransferase I (β4Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in
the presence of Mn2+ ion (Gal-T activity) and also transfers Glc from UDP-Glc to GlcNAc (Glc …

The structure and fold of the enzyme responsible for the biosynthesis of the
xenotransplantation antigen, namely pig α3 galactosyltransferase, has been studied by …

The crystal structure of the catalytic domain of bovine β1, 4-galactosyltransferase (Gal-T1) co-
crystallized with UDP-Gal and MnCl2 has been solved at 2.8 Å resolution. The structure not …

Beta-1, 4-galactosylransferase (β4Gal-T1) participates in the synthesis of Galβ1-4-GlcNAc-
disaccharide unit of glycoconjugates. It is a trans-Golgi glycosyltransferase (Glyco-T) with a …

β-1, 4-Galactosyltransferase (β4Gal-T1) in the presence of manganese ion transfers
galactose from UDP-galactose (UDP-Gal) to N-acetylglucosamine (GlcNAc) that is either …