Safety of erlotinib in TRUST, a phase IV trial in patients with advanced non-small cell lung cancer (NSCLC): initial results from the East/South East (E/SE) Asian …

Y Wu, L Zhang, J Siu-Kie Au, A Cheng… - Journal of Clinical …, 2007 - ascopubs.org
18018 Background: Erlotinib significantly improved survival versus placebo and was well
tolerated in patients (pts) with previously treated advanced NSCLC in the phase III BR. 21 …

Erlotinib in non-small cell lung cancer (NSCLC): Interim safety analysis of the TRUST study

U Gatzemeier, A Ardizzoni, K Horwood… - Journal of Clinical …, 2007 - ascopubs.org
7645 Background: In patients (pts) with relapsed NSCLC, erlotinib 150 mg/d significantly
prolonged survival, delayed symptom progression, and improved quality of life versus …

The global TRUST study of erlotinib in advanced non-small-cell lung cancer (NSCLC)

H Groen, OG Arrieta, H Riska, K Horwood… - Journal of Clinical …, 2008 - ascopubs.org
19000 Background: Erlotinib significantly improved survival and quality of life while delaying
symptom progression compared with placebo in patients (pts) with relapsed NSCLC …

Efficacy and safety of erlotinib in> 1200 East/South-East (E/SE) Asian patients (pts) with advanced non-small-cell lung cancer (NSCLC)

TS Mok, C Zhou, S Kim, Y Wu, R Perng - Journal of Clinical Oncology, 2008 - ascopubs.org
19001 Background: The open-label, global phase IV TRUST study provided erlotinib for pts
with advanced NSCLC. Methods: Eligible pts had stage IIIB/IV NSCLC and had either failed …

Efficacy of erlotinib on advanced non-small cell lung cancer

HY Zhao, Y Zhang, H Huang, LK Chen… - Ai zheng= Aizheng …, 2008 - europepmc.org
Methods An open labeled, expanded access program (EAP) was conducted on 44
pathologically confirmed advanced NSCLC patients who had received at least one regimen …

[HTML][HTML] Efficacy and safety of erlotinib in 1242 East/South-East Asian patients with advanced non-small cell lung cancer

T Mok, Y Wu, JS Au, C Zhou, L Zhang, RP Perng… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor that
significantly increases survival for patients with previously treated advanced non-small cell …

A randomized placebo-controlled trial of erlotinib in patients with advanced non-small cell lung cancer (NSCLC) following failure of 1st line or 2nd line chemotherapy …

FA Shepherd, J Pereira, TE Ciuleanu… - Journal of Clinical …, 2004 - ascopubs.org
7022 Background: In phase II studies, erlotinib has shown single agent activity in a number
of tumor types, including NSCLC. NCIC CTG BR. 21 is a randomized, placebo-controlled …

B3-06: Interim safety results from TRUST, a global open-label study of erlotinib in patients with advanced non-small-cell lung cancer (NSCLC)

A Ardizzoni, E Razis, M Lichinitser, U Yilmaz… - Journal of Thoracic …, 2007 - jto.org
Background: In the BR. 21 phase III placebo-controlled study (Shepherd et al. NEJM 2005;
353: 123-132), erlotinib (Tarceva®) was well tolerated and significantly improved survival …

[PDF][PDF] Efficacy of Erlotinib in patients (PTS) with advanced non-small-cell lung cancer (NSCLC) relative to clinical charesteristics: subset analyses from the trust study

S Allan, L BOSQUEE, A Franke, R Pirker… - American Journal of …, 2008 - orbi.uliege.be
Background: Erlotinib is proven to prolong survival, delay symptom progression and improve
quality of life for pts with advanced NSCLC (Shepherd et al. N Engl J Med 2005; 353: 123 …

[HTML][HTML] Postmarketing surveillance study of erlotinib in Japanese patients with non–small-cell lung cancer (NSCLC): an interim analysis of 3488 patients …

K Nakagawa, S Kudoh, Y Ohe, T Johkoh… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Interstitial lung disease (ILD) is an adverse drug reaction (ADR) of concern in
Japanese patients with non–small-cell lung cancer (NSCLC) receiving erlotinib. To …